Quantum dots, lighting up the research and development of nanomedicine

YIC-IR > 中国科学院海岸带环境过程与生态修复重点实验室 > 海岸带环境工程技术研究与发展中心

	Quantum dots, lighting up the research and development of nanomedicine
	Wang, Yunqing; Chen, Lingxin1
发表期刊	NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE
ISSN	1549-9634
	2011-08-01
卷号	7 期号:4 页码:385-402
关键词	Quantum Dots Nanomedicine Fluorescence Imaging Multifunctional Drug Delivery System
产权排序	[Chen, LX] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China; Chinese Acad Sci, Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China; Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai, Peoples R China
通讯作者	Chen, LX, Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China. lxchen@yic.ac.cn
作者部门	环境化学实验室
英文摘要	Quantum dots (QDs) have proven themselves as powerful inorganic fluorescent probes, especially for long term, multiplexed imaging and detection. The newly developed QDs labeling techniques have facilitated the study of drug delivery on the level of living cells and small animals. Moreover, based on QDs and fluorescence imaging system, multifunctional nanocomplex integrated targeting, imaging and therapeutic functionalities have become effective materials for synchronous cancer diagnosis and treatment. In this review, we will summarize the recent advances of QDs in the research of drug delivery system from the following aspects: surface modification strategies of QDs for drug delivery, QDs as drug nanocarriers, QD-labeled drug nanocarriers, QD-based fluorescence resonance energy transfer (FRET) technique for drug release study as well as the development of multifunctional nanomedicines. Possible perspective in this field will also be discussed. From the Clinical Editor: This review discusses the role and significance of quantum dots (QDs) from the following aspects: surface modification strategies of QDs for drug delivery, QDs as drug nanocarriers, QD-labeled drug nanocarriers, QD-based fluorescence resonance energy transfer (FRET) technique for drug release study as well as the development of multifunctional nanomedicines. (C) 2011 Elsevier Inc. All rights reserved.; Quantum dots (QDs) have proven themselves as powerful inorganic fluorescent probes, especially for long term, multiplexed imaging and detection. The newly developed QDs labeling techniques have facilitated the study of drug delivery on the level of living cells and small animals. Moreover, based on QDs and fluorescence imaging system, multifunctional nanocomplex integrated targeting, imaging and therapeutic functionalities have become effective materials for synchronous cancer diagnosis and treatment. In this review, we will summarize the recent advances of QDs in the research of drug delivery system from the following aspects: surface modification strategies of QDs for drug delivery, QDs as drug nanocarriers, QD-labeled drug nanocarriers, QD-based fluorescence resonance energy transfer (FRET) technique for drug release study as well as the development of multifunctional nanomedicines. Possible perspective in this field will also be discussed.
文章类型	Review
资助机构	National Natural Science Foundation of China[20975089]; Chinese Academy of Sciences[KZCX2-EW-206]; Department of Science and Technology of Shandong Province of China[2008GG20005005]
收录类别	SCI
语种	英语
关键词[WOS]	FREE POLY(LACTIDE-CO-GLYCOLIDE) NANOPARTICLES ; HYALURONIC-ACID DERIVATIVES ; RESONANCE ENERGY-TRANSFER ; GROWTH-FACTOR RECEPTOR ; TUMOR-CELL UPTAKE ; IN-VIVO ; DRUG-DELIVERY ; LIVING CELLS ; CARBON NANOTUBES ; SIRNA DELIVERY
研究领域[WOS]	Science & Technology - Other Topics ; Research & Experimental Medicine
WOS记录号	WOS:000293218800003
引用统计	被引频次：216[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.yic.ac.cn/handle/133337/5111
专题	中国科学院海岸带环境过程与生态修复重点实验室_海岸带环境工程技术研究与发展中心中国科学院海岸带环境过程与生态修复重点实验室
作者单位	1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China 2.Chinese Acad Sci, Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China 3.Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai, Peoples R China
推荐引用方式 GB/T 7714	Wang, Yunqing,Chen, Lingxin. Quantum dots, lighting up the research and development of nanomedicine[J]. NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE,2011,7(4):385-402.
APA	Wang, Yunqing,&Chen, Lingxin.(2011).Quantum dots, lighting up the research and development of nanomedicine.NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE,7(4),385-402.
MLA	Wang, Yunqing,et al."Quantum dots, lighting up the research and development of nanomedicine".NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE 7.4(2011):385-402.

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