Off-On based fluorescent chemosensor for Cu(2+) in aqueous media and living cells | |
Yu, Chunwei1,4; Chen, Lingxin1; Zhang, Jun3; Li, Jinhua1; Liu, Ping1; Wang, Wenhai1; Yan, Bing2 | |
发表期刊 | TALANTA |
ISSN | 0039-9140 |
2011 | |
卷号 | 85期号:3页码:1627-1633 |
关键词 | Cu(2+) Fluorescent Chemosensor Rhodamine b Fluorescence Imaging Living Cells |
研究领域 | Chemistry |
DOI | 10.1016/j.talanta.2011.06.057 |
产权排序 | [Yu, CW; Chen, LX; Li, JH; Liu, P; Wang, WH] Chinese Acad Sci, Key Lab Coastal Zone Environm Proc, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China; [Yan, B] Shandong Univ, Sch Chem & Chem Engn, Jinan 250100, Peoples R China; [Zhang, J] Hainan Med Univ, Sch Trop & Lab Med, Haikou 571101, Peoples R China; [Yu, CW] Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China |
作者部门 | 环境化学实验室 |
英文摘要 | A novel Cu(2+)-specific "off-on" fluorescent chemosensor of naphthalimide modified rhodamine B (naphthalimide modified rhodamine B chemosensor, NRC) was designed and synthesized, based on the equilibrium between the spirolactam (non-fluorescence) and the ring-opened amide (fluorescence). The chemosensor NRC showed high Cu(2+)-selective fluorescence enhancement over commonly coexistent metal ions or anions in neutral aqueous media. The limit of detection (LOD) based on 3 x delta(blank)/k was obtained as low as 0.18 mu M of Cu(2+), as well as an excellent linearity of 0.05-4.5 mu M (R=0.999), indicating the chemosensor of high sensitivity and wide quantitation range. And also the coordination mode with 1:1 stoichiometry was proposed between NRC and Cu(2+). In addition, the effects of pH, co-existing metal ions and anions, and the reversibility were investigated in detail. It was also demonstrated that the NRC could be used as an excellent "off-on" fluorescent chemosensor for the measurement of Cu(2+) in living cells with satisfying results, which further displayed its valuable applications in biological systems. (C) 2011 Elsevier B.V. All rights reserved. |
资助机构 | National Natural Science Foundation of China[20975089, 90913006, 21077068] ; Chinese Academy of Sciences[KZCX2-EW-206] ; National Basic Research Program of China[2010CB933504] ; Department of Science and Technology of Shandong Province[2008GG20005005] ; Research and Training Foundation of Hainan Medical University[HY2010-004] |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000294092800059 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.yic.ac.cn/handle/133337/5105 |
专题 | 中国科学院海岸带环境过程与生态修复重点实验室_海岸带环境工程技术研究与发展中心 中国科学院海岸带环境过程与生态修复重点实验室 |
通讯作者 | Chen, Lingxin; Yan, Bing |
作者单位 | 1. Chinese Acad Sci, Key Lab Coastal Zone Environm Proc, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res 2.Shandong Univ, Sch Chem & Chem Engn. 3.Hainan Med Univ, Sch Trop & Lab Med. 4.Chinese Acad Sci, Grad Uni. |
推荐引用方式 GB/T 7714 | Yu, Chunwei,Chen, Lingxin,Zhang, Jun,et al. Off-On based fluorescent chemosensor for Cu(2+) in aqueous media and living cells[J]. TALANTA,2011,85(3):1627-1633. |
APA | Yu, Chunwei.,Chen, Lingxin.,Zhang, Jun.,Li, Jinhua.,Liu, Ping.,...&Yan, Bing.(2011).Off-On based fluorescent chemosensor for Cu(2+) in aqueous media and living cells.TALANTA,85(3),1627-1633. |
MLA | Yu, Chunwei,et al."Off-On based fluorescent chemosensor for Cu(2+) in aqueous media and living cells".TALANTA 85.3(2011):1627-1633. |
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