Off-On based fluorescent chemosensor for Cu(2+) in aqueous media and living cells
Yu, Chunwei ; Chen, Lingxin ; Zhang, Jun ; Li, Jinhua ; Liu, Ping ; Wang, Wenhai ; Yan, Bing
Source PublicationTALANTA
ISSN0039-9140
2011
Volume85Issue:3Pages:1627-1633
KeywordCu(2+) Fluorescent Chemosensor Rhodamine b Fluorescence Imaging Living Cells
Contribution Rank[Yu, CW; Chen, LX; Li, JH; Liu, P; Wang, WH] Chinese Acad Sci, Key Lab Coastal Zone Environm Proc, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China; [Yan, B] Shandong Univ, Sch Chem & Chem Engn, Jinan 250100, Peoples R China; [Zhang, J] Hainan Med Univ, Sch Trop & Lab Med, Haikou 571101, Peoples R China; [Yu, CW] Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
Corresponding AuthorChen, LX, Chinese Acad Sci, Key Lab Coastal Zone Environm Proc, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China. lxchen@yic.ac.cn ; dr.bingyan@gmail.com
Department环境化学实验室 
AbstractA novel Cu(2+)-specific "off-on" fluorescent chemosensor of naphthalimide modified rhodamine B (naphthalimide modified rhodamine B chemosensor, NRC) was designed and synthesized, based on the equilibrium between the spirolactam (non-fluorescence) and the ring-opened amide (fluorescence). The chemosensor NRC showed high Cu(2+)-selective fluorescence enhancement over commonly coexistent metal ions or anions in neutral aqueous media. The limit of detection (LOD) based on 3 x delta(blank)/k was obtained as low as 0.18 mu M of Cu(2+), as well as an excellent linearity of 0.05-4.5 mu M (R=0.999), indicating the chemosensor of high sensitivity and wide quantitation range. And also the coordination mode with 1:1 stoichiometry was proposed between NRC and Cu(2+). In addition, the effects of pH, co-existing metal ions and anions, and the reversibility were investigated in detail. It was also demonstrated that the NRC could be used as an excellent "off-on" fluorescent chemosensor for the measurement of Cu(2+) in living cells with satisfying results, which further displayed its valuable applications in biological systems. (C) 2011 Elsevier B.V. All rights reserved.
Funding OrganizationNational Natural Science Foundation of China[20975089, 90913006, 21077068]; Chinese Academy of Sciences[KZCX2-EW-206]; National Basic Research Program of China[2010CB933504]; Department of Science and Technology of Shandong Province[2008GG20005005]; Research and Training Foundation of Hainan Medical University[HY2010-004]
Indexed BySCI
Language英语
Document Type期刊论文
Identifierhttp://ir.yic.ac.cn/handle/133337/5105
Collection中科院海岸带环境过程与生态修复重点实验室_环境化学实验室
中科院海岸带环境过程与生态修复重点实验室
Recommended Citation
GB/T 7714
Yu, Chunwei,Chen, Lingxin,Zhang, Jun,et al. Off-On based fluorescent chemosensor for Cu(2+) in aqueous media and living cells[J]. TALANTA,2011,85(3):1627-1633.
APA Yu, Chunwei.,Chen, Lingxin.,Zhang, Jun.,Li, Jinhua.,Liu, Ping.,...&Yan, Bing.(2011).Off-On based fluorescent chemosensor for Cu(2+) in aqueous media and living cells.TALANTA,85(3),1627-1633.
MLA Yu, Chunwei,et al."Off-On based fluorescent chemosensor for Cu(2+) in aqueous media and living cells".TALANTA 85.3(2011):1627-1633.
Files in This Item: Download All
File Name/Size DocType Version Access License
Off-On based fluores(662KB) 开放获取--View Download
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Yu, Chunwei]'s Articles
[Chen, Lingxin]'s Articles
[Zhang, Jun]'s Articles
Baidu academic
Similar articles in Baidu academic
[Yu, Chunwei]'s Articles
[Chen, Lingxin]'s Articles
[Zhang, Jun]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Yu, Chunwei]'s Articles
[Chen, Lingxin]'s Articles
[Zhang, Jun]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: Off-On based fluorescent chemosensor for Cu(2+) in aqueous media and living cells.pdf
Format: Adobe PDF
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.