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题名:
Cancer-Targeting Multifunctionalized Gold Nanoparticles in Imaging and Therapy
作者: Jiao, P. F.2; Zhou, H. Y.1; Chen, L. X.3; Yan, B.1,4
刊名: CURRENT MEDICINAL CHEMISTRY
ISSN号: 0929-8673
出版日期: 2011-05-01
卷号: 18, 期号:14, 页码:2086-2102
关键词: Gold nanoparticles ; targeting moieties ; therapeutic payloads ; conjugation methods ; cancer imaging ; cancer therapy
学科分类: Biochemistry & Molecular Biology; Chemistry ; Medicinal; Pharmacology & Pharmacy
产权排序: [Zhou, H. Y.; Yan, B.] St Jude Childrens Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USA; [Jiao, P. F.] Shandong Univ, Sch Pharmaceut Sci, Jinan 250012, Shandong, Peoples R China; [Chen, L. X.] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Shandong, Peoples R China; [Yan, B.] Shandong Univ, Sch Chem & Chem Engn, Jinan 250100, Peoples R China
通讯作者: Yan, B, Shandong Univ, Sch Chem & Chem Engn, Jinan 250100, Peoples R China.Dr.bingyan@gmail.com
作者部门: 环境化学实验室 
中文摘要: Nanotechnology has provided many promising nanoplatforms for targeted cancer imaging and therapy. Among these platforms, gold nanoparticles (GNPs) play a unique role in medicine because of their excellent physical and chemical properties. To expand the applications of GNPs in medicine, amounts of targeting moieties, imaging labels, and therapeutic agents have been integrated into these particles to form multifunctionalized GNPs. In this review, we highlight recent advances of the fabrication of cancer-targeting multifunctionalized GNPs and their applications in imaging and therapy.
英文摘要: Nanotechnology has provided many promising nanoplatforms for targeted cancer imaging and therapy. Among these platforms, gold nanoparticles (GNPs) play a unique role in medicine because of their excellent physical and chemical properties. To expand the applications of GNPs in medicine, amounts of targeting moieties, imaging labels, and therapeutic agents have been integrated into these particles to form multifunctionalized GNPs. In this review, we highlight recent advances of the fabrication of cancer-targeting multifunctionalized GNPs and their applications in imaging and therapy.
研究领域[WOS]: Biochemistry & Molecular Biology ; Pharmacology & Pharmacy
关键词[WOS]: RECEPTOR-MEDIATED ENDOCYTOSIS ; GROWTH-FACTOR RECEPTOR ; DRUG-DELIVERY ; PHOTOTHERMAL ABLATION ; CONTRAST AGENTS ; IN-VITRO ; CONTROLLED-RELEASE ; OPTICAL-PROPERTIES ; RAMAN-SCATTERING ; FACILE SYNTHESIS
文章类型: Review
收录类别: SCI
语种: 英语
WOS记录号: WOS:000290612000005
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.yic.ac.cn/handle/133337/4838
Appears in Collections:环境化学实验室_期刊论文

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作者单位: 1.St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USA
2.Shandong Univ, Sch Pharmaceut Sci, Jinan 250012, Shandong, Peoples R China
3.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Shandong, Peoples R China
4.Shandong Univ, Sch Chem & Chem Engn, Jinan 250100, Peoples R China

Recommended Citation:
Jiao, P. F.,Zhou, H. Y.,Chen, L. X.,et al. Cancer-Targeting Multifunctionalized Gold Nanoparticles in Imaging and Therapy[J]. CURRENT MEDICINAL CHEMISTRY,2011,18(14):2086-2102.
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