Cancer-Targeting Multifunctionalized Gold Nanoparticles in Imaging and Therapy
Jiao, P. F.2; Zhou, H. Y.1; Chen, L. X.3; Yan, B.1,4
2011-05-01
Source PublicationCURRENT MEDICINAL CHEMISTRY
ISSN0929-8673
Volume18Issue:14Pages:2086-2102
Contribution Rank[Zhou, H. Y.; Yan, B.] St Jude Childrens Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USA; [Jiao, P. F.] Shandong Univ, Sch Pharmaceut Sci, Jinan 250012, Shandong, Peoples R China; [Chen, L. X.] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Shandong, Peoples R China; [Yan, B.] Shandong Univ, Sch Chem & Chem Engn, Jinan 250100, Peoples R China
AbstractNanotechnology has provided many promising nanoplatforms for targeted cancer imaging and therapy. Among these platforms, gold nanoparticles (GNPs) play a unique role in medicine because of their excellent physical and chemical properties. To expand the applications of GNPs in medicine, amounts of targeting moieties, imaging labels, and therapeutic agents have been integrated into these particles to form multifunctionalized GNPs. In this review, we highlight recent advances of the fabrication of cancer-targeting multifunctionalized GNPs and their applications in imaging and therapy.; Nanotechnology has provided many promising nanoplatforms for targeted cancer imaging and therapy. Among these platforms, gold nanoparticles (GNPs) play a unique role in medicine because of their excellent physical and chemical properties. To expand the applications of GNPs in medicine, amounts of targeting moieties, imaging labels, and therapeutic agents have been integrated into these particles to form multifunctionalized GNPs. In this review, we highlight recent advances of the fabrication of cancer-targeting multifunctionalized GNPs and their applications in imaging and therapy.
Corresponding AuthorYan, B, Shandong Univ, Sch Chem & Chem Engn, Jinan 250100, Peoples R China.Dr.bingyan@gmail.com
KeywordGold Nanoparticles Targeting Moieties Therapeutic Payloads Conjugation Methods Cancer Imaging Cancer Therapy
Department环境化学实验室 
Subject AreaBiochemistry & Molecular Biology ; Medicinal ; Chemistry ; Pharmacology & Pharmacy
Funding OrganizationNational Natural Science Foundation of China [30871943]; High Technology Research and Development Programme of China [2006AA09Z438]
Indexed BySCI
WOS KeywordRECEPTOR-MEDIATED ENDOCYTOSIS ; GROWTH-FACTOR RECEPTOR ; DRUG-DELIVERY ; PHOTOTHERMAL ABLATION ; CONTRAST AGENTS ; IN-VITRO ; CONTROLLED-RELEASE ; OPTICAL-PROPERTIES ; RAMAN-SCATTERING ; FACILE SYNTHESIS
SubtypeReview
Language英语
WOS Research AreaBiochemistry & Molecular Biology ; Pharmacology & Pharmacy
WOS IDWOS:000290612000005
Citation statistics
Document Type期刊论文
Identifierhttp://ir.yic.ac.cn/handle/133337/4837
Collection中科院海岸带环境过程与生态修复重点实验室_环境化学实验室
Affiliation1.St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USA
2.Shandong Univ, Sch Pharmaceut Sci, Jinan 250012, Shandong, Peoples R China
3.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Shandong, Peoples R China
4.Shandong Univ, Sch Chem & Chem Engn, Jinan 250100, Peoples R China
Recommended Citation
GB/T 7714
Jiao, P. F.,Zhou, H. Y.,Chen, L. X.,et al. Cancer-Targeting Multifunctionalized Gold Nanoparticles in Imaging and Therapy[J]. CURRENT MEDICINAL CHEMISTRY,2011,18(14):2086-2102.
APA Jiao, P. F.,Zhou, H. Y.,Chen, L. X.,&Yan, B..(2011).Cancer-Targeting Multifunctionalized Gold Nanoparticles in Imaging and Therapy.CURRENT MEDICINAL CHEMISTRY,18(14),2086-2102.
MLA Jiao, P. F.,et al."Cancer-Targeting Multifunctionalized Gold Nanoparticles in Imaging and Therapy".CURRENT MEDICINAL CHEMISTRY 18.14(2011):2086-2102.
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