Cancer-Targeting Multifunctionalized Gold Nanoparticles in Imaging and Therapy
Jiao, P. F.2; Zhou, H. Y.1; Chen, L. X.3; Yan, B.1,4
2011-05-01
发表期刊CURRENT MEDICINAL CHEMISTRY
ISSN0929-8673
卷号18期号:14页码:2086-2102
产权排序[Zhou, H. Y.; Yan, B.] St Jude Childrens Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USA; [Jiao, P. F.] Shandong Univ, Sch Pharmaceut Sci, Jinan 250012, Shandong, Peoples R China; [Chen, L. X.] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Shandong, Peoples R China; [Yan, B.] Shandong Univ, Sch Chem & Chem Engn, Jinan 250100, Peoples R China
摘要Nanotechnology has provided many promising nanoplatforms for targeted cancer imaging and therapy. Among these platforms, gold nanoparticles (GNPs) play a unique role in medicine because of their excellent physical and chemical properties. To expand the applications of GNPs in medicine, amounts of targeting moieties, imaging labels, and therapeutic agents have been integrated into these particles to form multifunctionalized GNPs. In this review, we highlight recent advances of the fabrication of cancer-targeting multifunctionalized GNPs and their applications in imaging and therapy.; Nanotechnology has provided many promising nanoplatforms for targeted cancer imaging and therapy. Among these platforms, gold nanoparticles (GNPs) play a unique role in medicine because of their excellent physical and chemical properties. To expand the applications of GNPs in medicine, amounts of targeting moieties, imaging labels, and therapeutic agents have been integrated into these particles to form multifunctionalized GNPs. In this review, we highlight recent advances of the fabrication of cancer-targeting multifunctionalized GNPs and their applications in imaging and therapy.
通讯作者Yan, B, Shandong Univ, Sch Chem & Chem Engn, Jinan 250100, Peoples R China.Dr.bingyan@gmail.com
关键词Gold Nanoparticles Targeting Moieties Therapeutic Payloads Conjugation Methods Cancer Imaging Cancer Therapy
作者部门环境化学实验室 
学科领域Biochemistry & Molecular Biology ; Medicinal ; Chemistry ; Pharmacology & Pharmacy
项目资助者National Natural Science Foundation of China [30871943]; High Technology Research and Development Programme of China [2006AA09Z438]
收录类别SCI
关键词[WOS]RECEPTOR-MEDIATED ENDOCYTOSIS ; GROWTH-FACTOR RECEPTOR ; DRUG-DELIVERY ; PHOTOTHERMAL ABLATION ; CONTRAST AGENTS ; IN-VITRO ; CONTROLLED-RELEASE ; OPTICAL-PROPERTIES ; RAMAN-SCATTERING ; FACILE SYNTHESIS
文章类型Review
语种英语
WOS研究方向Biochemistry & Molecular Biology ; Pharmacology & Pharmacy
WOS记录号WOS:000290612000005
引用统计
文献类型期刊论文
条目标识符http://ir.yic.ac.cn/handle/133337/4837
专题中科院海岸带环境过程与生态修复重点实验室_环境化学实验室
作者单位1.St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USA
2.Shandong Univ, Sch Pharmaceut Sci, Jinan 250012, Shandong, Peoples R China
3.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Shandong, Peoples R China
4.Shandong Univ, Sch Chem & Chem Engn, Jinan 250100, Peoples R China
推荐引用方式
GB/T 7714
Jiao, P. F.,Zhou, H. Y.,Chen, L. X.,et al. Cancer-Targeting Multifunctionalized Gold Nanoparticles in Imaging and Therapy[J]. CURRENT MEDICINAL CHEMISTRY,2011,18(14):2086-2102.
APA Jiao, P. F.,Zhou, H. Y.,Chen, L. X.,&Yan, B..(2011).Cancer-Targeting Multifunctionalized Gold Nanoparticles in Imaging and Therapy.CURRENT MEDICINAL CHEMISTRY,18(14),2086-2102.
MLA Jiao, P. F.,et al."Cancer-Targeting Multifunctionalized Gold Nanoparticles in Imaging and Therapy".CURRENT MEDICINAL CHEMISTRY 18.14(2011):2086-2102.
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