| Synthesis of water-soluble quaternized chitosans and their antitumor activity | |
| Dong,Fang ; Xue,Qinzhao ; Liu,Jingli ; Ren,Jianming ; Guo,Zhanyong | |
| 通讯作者 | Dong,F. |
| 2010 | |
| 会议名称 | 4th International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2010 |
| 会议日期 | 2010-06-18 |
| 会议地点 | . |
| ISBN号 | ISBN-13:9781424447138 |
| 产权排序 | (1) Yantai Institute of Coastal Zone Research for Sustainable Development, CAS, Yantai, 264003, China; (2) Institute of Oceanology, CAS, Qingdao, 266071, China; (3) Graduate School of the Chinese Academy of Sciences, Beijing, China |
| 关键词 | Bioinformatics Chitin Chitosan Hydrogels Hydrogen Peroxide Multilayers Oxidation |
| 摘要 | water-soluble low-molecular-weight chitosan(LCTS) was prepared by hydrogen peroxide oxidation method and their quaternized derivatives(QLCTS) was also synthesized using previous methods. Their antitumor activity was studied, and the results showed that the LMW and its quaternized derivatives inhibited the growth of pancreatic carcinoma cell strain PANC-1 in vitro, and the inhibitory rate reached 59.2%. © 2010 IEEE. |
| 作者部门 | 污染过程与控制实验室 |
| 学科领域 | 有机化学 |
| URL | 查看原文 |
| 收录类别 | EI |
| 语种 | 英语 |
| 文献类型 | 会议论文 |
| 条目标识符 | http://ir.yic.ac.cn/handle/133337/4779 |
| 专题 | 中国科学院海岸带环境过程与生态修复重点实验室_污染过程与控制实验室 |
| 推荐引用方式 GB/T 7714 | Dong,Fang,Xue,Qinzhao,Liu,Jingli,et al. Synthesis of water-soluble quaternized chitosans and their antitumor activity[C]:IEEE Computer Society, 445 Hoes Lane - P.O.Box 1331, Piscataway, NJ 08855-1331, United States,2010. |
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