| The hydroxyl radical scavenging activity of chitosan, hyaluronan, starch and their O-carboxymethylated derivatives | |
Yang, Shaoli ; Guo, Zhanyong; Miao, Fengping; Xue, Qinzhao; Qin, Song
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| 发表期刊 | CARBOHYDRATE POLYMERS
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| ISSN | 0144-8617 |
| 2010-11-11 | |
| 卷号 | 82期号:4页码:1043-1045 |
| 关键词 | Antioxidant Activity Carboxymethylated Polysaccharides Polysaccharides |
| 产权排序 | [Yang, Shaoli; Guo, Zhanyong; Miao, Fengping; Xue, Qinzhao; Qin, Song] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China |
| 通讯作者 | Guo, ZY, Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China |
| 作者部门 | 生物资源实验室 |
| 英文摘要 | In order to study the effect of active hydroxyl and amino groups on scavenging activity against hydroxyl radicals of polysaccharides, three kinds of carboxymethylated polysaccharides (carboxymethyl chitosan (O-CM-chitosan), carboxymethyl hyaluronan (CMHA), and carboxymethyl starch (CMS)) were prepared and their antioxidant activities against hydroxyl radicals were assessed, respectively. Results showed that O-CM-chitosan had lower scavenging ability on hydroxyl radicals than chitosan. CMHA and CMS had the same tendency. For the three kinds of polysaccharides, scavenging ability on hydroxyl radicals was found to be in the order of chitosan > HA > starch. The scavenging ability of carboxymethylated polysaccharides had the same order as related to its corresponding polysaccharides at higher concentrations (>= 0.8mg/ml). There were not only hydroxyl groups but also amino or acetamino (CH3CONH-) groups in the molecules of chitosan and HA, but only hydroxyl group for starch. It was suggested that the sequence influence the scavenging activity against hydroxyl radicals might be amino group > acetamide group > hydroxyl group. (C) 2010 Elsevier Ltd. All rights reserved.; In order to study the effect of active hydroxyl and amino groups on scavenging activity against hydroxyl radicals of polysaccharides, three kinds of carboxymethylated polysaccharides (carboxymethyl chitosan (O-CM-chitosan), carboxymethyl hyaluronan (CMHA), and carboxymethyl starch (CMS)) were prepared and their antioxidant activities against hydroxyl radicals were assessed, respectively. Results showed that O-CM-chitosan had lower scavenging ability on hydroxyl radicals than chitosan. CMHA and CMS had the same tendency. For the three kinds of polysaccharides, scavenging ability on hydroxyl radicals was found to be in the order of chitosan > HA > starch. The scavenging ability of carboxymethylated polysaccharides had the same order as related to its corresponding polysaccharides at higher concentrations (>= 0.8mg/ml). There were not only hydroxyl groups but also amino or acetamino (CH(3)CONH-) groups in the molecules of chitosan and HA, but only hydroxyl group for starch. It was suggested that the sequence influence the scavenging activity against hydroxyl radicals might be amino group > acetamide group > hydroxyl group. (C) 2010 Elsevier Ltd. All rights reserved. |
| 文章类型 | Article |
| 资助机构 | Chinese Academy of Sciences [kzcx2-yw-225]; foundation of Special Prize of President Scholarship for Postgraduate Students of Chinese Academy of Sciences |
| 收录类别 | SCI |
| 语种 | 英语 |
| 研究领域[WOS] | Chemistry ; Polymer Science |
| WOS记录号 | WOS:000283042100003 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.yic.ac.cn/handle/133337/3775 |
| 专题 | 海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室 |
| 作者单位 | Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yang, Shaoli,Guo, Zhanyong,Miao, Fengping,et al. The hydroxyl radical scavenging activity of chitosan, hyaluronan, starch and their O-carboxymethylated derivatives[J]. CARBOHYDRATE POLYMERS,2010,82(4):1043-1045. |
| APA | Yang, Shaoli,Guo, Zhanyong,Miao, Fengping,Xue, Qinzhao,&Qin, Song.(2010).The hydroxyl radical scavenging activity of chitosan, hyaluronan, starch and their O-carboxymethylated derivatives.CARBOHYDRATE POLYMERS,82(4),1043-1045. |
| MLA | Yang, Shaoli,et al."The hydroxyl radical scavenging activity of chitosan, hyaluronan, starch and their O-carboxymethylated derivatives".CARBOHYDRATE POLYMERS 82.4(2010):1043-1045. |
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