Nanomaterial-assisted aptamers for optical sensing
Wang, Guoqing1; Wang, Yunqing1; Chen, Lingxin1; Choo, Jaebum2
2010-04-15
发表期刊BIOSENSORS & BIOELECTRONICS
ISSN0956-5663
卷号25期号:8页码:1859-1868
产权排序[Wang, Guoqing; Wang, Yunqing; Chen, Lingxin] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China; [Choo, Jaebum] Hanyang Univ, Dept Bionano Engn, Ansan 426791, South Korea
摘要Aptamers are single-strand DNA or RNA selected in vitro that bind specifically with a broad range of targets from metal ions, organic molecules, to proteins, cells and microorganisms. As an emerging class of recognition elements, aptamers offer remarkable convenience in the design and modification of their structures, which has motivated them to generate a great variety of aptamer sensors (aptasensors) that exhibit high sensitivity as well as specificity. On the other hand, the development of nanoscience and nanotechnology has generated nanomaterials with novel properties compared with their counterparts in macroscale. By integrating their strengths of both fields, recently, versatile aptamers coupling with novel nanomaterials for designing nanomaterial-assisted aptasensors (NAAs) make the combinations universal strategies for sensitive optical sensing. NAAs have been considered as an excellent sensing platform and found wide applications in analytical community. In this review, we summarize recent advances in the development of various optical NAAs, employing various detection techniques including colorimetry, fluorometry, surface-enhanced Raman scattering (SERS), magnetic resonance imaging (MRI) and surface plasmon resonance (SPR). (c) 2009 Elsevier B.V. All rights reserved.; Aptamers are single-strand DNA or RNA selected in vitro that bind specifically with a broad range of targets from metal ions, organic molecules, to proteins, cells and microorganisms. As an emerging class of recognition elements, aptamers offer remarkable convenience in the design and modification of their structures, which has motivated them to generate a great variety of aptamer sensors (aptasensors) that exhibit high sensitivity as well as specificity. On the other hand, the development of nanoscience and nanotechnology has generated nanomaterials with novel properties compared with their counterparts in macroscale. By integrating their strengths of both fields, recently, versatile aptamers coupling with novel nanomaterials for designing nanomaterial-assisted aptasensors (NAAs) make the combinations universal strategies for sensitive optical sensing. NAAs have been considered as an excellent sensing platform and found wide applications in analytical community. In this review, we summarize recent advances in the development of various optical NAAs, employing various detection techniques including colorimetry, fluorometry, surface-enhanced Raman scattering (SERS), magnetic resonance imaging (MRI) and surface plasmon resonance (SPR). (c) 2009 Elsevier B.V. All rights reserved.
通讯作者Chen, LX, Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China
关键词Aptamer Nanomaterial Aptamer Sensor Optical Sensing
作者部门环境化学实验室 
学科领域Biophysics ; Biotechnology & Applied Microbiology ; Chemistry, Analytical ; Electrochemistry ; Nanoscience & Nanotechnology
项目资助者National Natural Science Foundation of China [20975089]; Department of Science and Technology of Shandong Province of China [2008GG20005005]; Chinese Academy of Sciences [20090462]; National Research Foundation of Korea [R11-2009-044-1002-0, K20904000004-09A050000410]; KRIBB ; Ministry of Knowledge Economy (MKE) ; Korea Industrial Technology Foundation (KOTEF)
URL查看原文
收录类别SCI
关键词[WOS]FUNCTIONALIZED GOLD NANOPARTICLES ; ENHANCED RAMAN-SCATTERING ; SURFACE-PLASMON RESONANCE ; IRON-OXIDE NANOPARTICLES ; QUANTUM-DOT ; COLORIMETRIC DETECTION ; PROTEIN-DETECTION ; CANCER-CELLS ; MICROFLUIDIC CHANNEL ; THROMBIN DETECTION
文章类型Review
语种英语
WOS研究方向Biophysics ; Biotechnology & Applied Microbiology ; Chemistry ; Electrochemistry ; Science & Technology - Other Topics
WOS记录号WOS:000276424200001
引用统计
文献类型期刊论文
条目标识符http://ir.yic.ac.cn/handle/133337/3721
专题中科院海岸带环境过程与生态修复重点实验室_环境化学实验室
作者单位1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China
2.Hanyang Univ, Dept Bionano Engn, Ansan 426791, South Korea
第一作者单位中国科学院烟台海岸带研究所
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Wang, Guoqing,Wang, Yunqing,Chen, Lingxin,et al. Nanomaterial-assisted aptamers for optical sensing[J]. BIOSENSORS & BIOELECTRONICS,2010,25(8):1859-1868.
APA Wang, Guoqing,Wang, Yunqing,Chen, Lingxin,&Choo, Jaebum.(2010).Nanomaterial-assisted aptamers for optical sensing.BIOSENSORS & BIOELECTRONICS,25(8),1859-1868.
MLA Wang, Guoqing,et al."Nanomaterial-assisted aptamers for optical sensing".BIOSENSORS & BIOELECTRONICS 25.8(2010):1859-1868.
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