Nanomaterial-assisted aptamers for optical sensing | |
Wang, Guoqing1; Wang, Yunqing1; Chen, Lingxin1; Choo, Jaebum2 | |
发表期刊 | BIOSENSORS & BIOELECTRONICS |
ISSN | 0956-5663 |
2010-04-15 | |
卷号 | 25期号:8页码:1859-1868 |
关键词 | Aptamer Nanomaterial Aptamer Sensor Optical Sensing |
产权排序 | [Wang, Guoqing; Wang, Yunqing; Chen, Lingxin] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China; [Choo, Jaebum] Hanyang Univ, Dept Bionano Engn, Ansan 426791, South Korea |
通讯作者 | Chen, LX, Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China |
作者部门 | 环境化学实验室 |
英文摘要 | Aptamers are single-strand DNA or RNA selected in vitro that bind specifically with a broad range of targets from metal ions, organic molecules, to proteins, cells and microorganisms. As an emerging class of recognition elements, aptamers offer remarkable convenience in the design and modification of their structures, which has motivated them to generate a great variety of aptamer sensors (aptasensors) that exhibit high sensitivity as well as specificity. On the other hand, the development of nanoscience and nanotechnology has generated nanomaterials with novel properties compared with their counterparts in macroscale. By integrating their strengths of both fields, recently, versatile aptamers coupling with novel nanomaterials for designing nanomaterial-assisted aptasensors (NAAs) make the combinations universal strategies for sensitive optical sensing. NAAs have been considered as an excellent sensing platform and found wide applications in analytical community. In this review, we summarize recent advances in the development of various optical NAAs, employing various detection techniques including colorimetry, fluorometry, surface-enhanced Raman scattering (SERS), magnetic resonance imaging (MRI) and surface plasmon resonance (SPR). (c) 2009 Elsevier B.V. All rights reserved.; Aptamers are single-strand DNA or RNA selected in vitro that bind specifically with a broad range of targets from metal ions, organic molecules, to proteins, cells and microorganisms. As an emerging class of recognition elements, aptamers offer remarkable convenience in the design and modification of their structures, which has motivated them to generate a great variety of aptamer sensors (aptasensors) that exhibit high sensitivity as well as specificity. On the other hand, the development of nanoscience and nanotechnology has generated nanomaterials with novel properties compared with their counterparts in macroscale. By integrating their strengths of both fields, recently, versatile aptamers coupling with novel nanomaterials for designing nanomaterial-assisted aptasensors (NAAs) make the combinations universal strategies for sensitive optical sensing. NAAs have been considered as an excellent sensing platform and found wide applications in analytical community. In this review, we summarize recent advances in the development of various optical NAAs, employing various detection techniques including colorimetry, fluorometry, surface-enhanced Raman scattering (SERS), magnetic resonance imaging (MRI) and surface plasmon resonance (SPR). (c) 2009 Elsevier B.V. All rights reserved. |
文章类型 | Review |
资助机构 | National Natural Science Foundation of China [20975089]; Department of Science and Technology of Shandong Province of China [2008GG20005005]; Chinese Academy of Sciences [20090462]; National Research Foundation of Korea [R11-2009-044-1002-0, K20904000004-09A050000410]; KRIBB ; Ministry of Knowledge Economy (MKE) ; Korea Industrial Technology Foundation (KOTEF) |
收录类别 | SCI |
语种 | 英语 |
关键词[WOS] | FUNCTIONALIZED GOLD NANOPARTICLES ; ENHANCED RAMAN-SCATTERING ; SURFACE-PLASMON RESONANCE ; IRON-OXIDE NANOPARTICLES ; QUANTUM-DOT ; COLORIMETRIC DETECTION ; PROTEIN-DETECTION ; CANCER-CELLS ; MICROFLUIDIC CHANNEL ; THROMBIN DETECTION |
研究领域[WOS] | Biophysics ; Biotechnology & Applied Microbiology ; Chemistry ; Electrochemistry ; Science & Technology - Other Topics |
WOS记录号 | WOS:000276424200001 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.yic.ac.cn/handle/133337/3721 |
专题 | 中国科学院海岸带环境过程与生态修复重点实验室_海岸带环境工程技术研究与发展中心 |
作者单位 | 1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China 2.Hanyang Univ, Dept Bionano Engn, Ansan 426791, South Korea |
推荐引用方式 GB/T 7714 | Wang, Guoqing,Wang, Yunqing,Chen, Lingxin,et al. Nanomaterial-assisted aptamers for optical sensing[J]. BIOSENSORS & BIOELECTRONICS,2010,25(8):1859-1868. |
APA | Wang, Guoqing,Wang, Yunqing,Chen, Lingxin,&Choo, Jaebum.(2010).Nanomaterial-assisted aptamers for optical sensing.BIOSENSORS & BIOELECTRONICS,25(8),1859-1868. |
MLA | Wang, Guoqing,et al."Nanomaterial-assisted aptamers for optical sensing".BIOSENSORS & BIOELECTRONICS 25.8(2010):1859-1868. |
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