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Aptamer-Nanoparticle-Based Optical Probes
Wang Guoqing; Chen Zhaopeng; Chen Lingxin
2010-03-01
发表期刊PROGRESS IN CHEMISTRY
ISSN1005-281X
卷号22期号:2-3页码:489-499
产权排序[Wang Guoqing; Chen Zhaopeng; Chen Lingxin] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China
摘要Aptamers are short single-stranded DNA (ssDNA) or RNA by in vitro screening of systematic evolution of ligands by exponential enrichment (SELEX). Based on their special structures which are easily rebuilt and modified, aptamers are of high affinity and specificity with a wide range of targets. These advantages have motivated aptamers to find broad applications for biomedicine, clinic diagnosis, drug discovery, environmental science and so on. Recently, aptamers integrated with nanotechnology have realized simple and rapid recognition of various targets with high sensitivity and selectivity owing to the novel optical, magnetic, electric, chemical and biological properties of nanomaterials. This paper reviews the latest advances and trends of aptamer-nanomaterial-based optical probes for biomolecules, metal ions and organic compounds, including colorimetry, fluoresence and surface-enhanced Raman spectroscopy (SERS).; Aptamers are short single-stranded DNA (ssDNA) or RNA by in vitro screening of systematic evolution of ligands by exponential enrichment (SELEX). Based on their special structures which are easily rebuilt and modified, aptamers are of high affinity and specificity with a wide range of targets. These advantages have motivated aptamers to find broad applications for biomedicine, clinic diagnosis, drug discovery, environmental science and so on. Recently, aptamers integrated with nanotechnology have realized simple and rapid recognition of various targets with high sensitivity and selectivity owing to the novel optical, magnetic, electric, chemical and biological properties of nanomaterials. This paper reviews the latest advances and trends of aptamer-nanomaterial-based optical probes for biomolecules, metal ions and organic compounds, including colorimetry, fluoresence and surface-enhanced Raman spectroscopy (SERS).
通讯作者Chen, LX, Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China
关键词Aptamer Nanoparticles Sensors Optical Probes
作者部门环境化学实验室 
学科领域Chemistry, Multidisciplinary
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收录类别SCI
关键词[WOS]ENHANCED RAMAN-SPECTROSCOPY ; FUNCTIONALIZED GOLD NANOPARTICLES ; FREE COLORIMETRIC DETECTION ; PROTEIN-DETECTION ; QUANTUM-DOT ; MICROFLUIDIC CHANNEL ; THROMBIN DETECTION ; AU NANOPARTICLES ; DNA APTAMER ; SENSOR
文章类型Article
语种英语
WOS研究方向Chemistry
WOS记录号WOS:000275994000031
引用统计
被引频次:7[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.yic.ac.cn/handle/133337/3710
专题环境化学实验室
作者单位Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China
第一作者单位中国科学院烟台海岸带研究所
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Wang Guoqing,Chen Zhaopeng,Chen Lingxin. Aptamer-Nanoparticle-Based Optical Probes[J]. PROGRESS IN CHEMISTRY,2010,22(2-3):489-499.
APA Wang Guoqing,Chen Zhaopeng,&Chen Lingxin.(2010).Aptamer-Nanoparticle-Based Optical Probes.PROGRESS IN CHEMISTRY,22(2-3),489-499.
MLA Wang Guoqing,et al."Aptamer-Nanoparticle-Based Optical Probes".PROGRESS IN CHEMISTRY 22.2-3(2010):489-499.
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