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题名:
Aptamer-Nanoparticle-Based Optical Probes
作者: Wang Guoqing; Chen, ZhaoPeng(陈兆鹏); Chen Lingxin
刊名: PROGRESS IN CHEMISTRY
ISSN号: 1005-281X
出版日期: 2010-03-01
卷号: 22, 期号:2-3, 页码:489-499
关键词: aptamer ; nanoparticles ; sensors ; optical probes
学科分类: Chemistry, Multidisciplinary
产权排序: [Wang Guoqing; Chen Zhaopeng; Chen Lingxin] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China
通讯作者: Chen, LX, Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China
作者部门: 环境化学实验室 
中文摘要: Aptamers are short single-stranded DNA (ssDNA) or RNA by in vitro screening of systematic evolution of ligands by exponential enrichment (SELEX). Based on their special structures which are easily rebuilt and modified, aptamers are of high affinity and specificity with a wide range of targets. These advantages have motivated aptamers to find broad applications for biomedicine, clinic diagnosis, drug discovery, environmental science and so on. Recently, aptamers integrated with nanotechnology have realized simple and rapid recognition of various targets with high sensitivity and selectivity owing to the novel optical, magnetic, electric, chemical and biological properties of nanomaterials. This paper reviews the latest advances and trends of aptamer-nanomaterial-based optical probes for biomolecules, metal ions and organic compounds, including colorimetry, fluoresence and surface-enhanced Raman spectroscopy (SERS).
英文摘要: Aptamers are short single-stranded DNA (ssDNA) or RNA by in vitro screening of systematic evolution of ligands by exponential enrichment (SELEX). Based on their special structures which are easily rebuilt and modified, aptamers are of high affinity and specificity with a wide range of targets. These advantages have motivated aptamers to find broad applications for biomedicine, clinic diagnosis, drug discovery, environmental science and so on. Recently, aptamers integrated with nanotechnology have realized simple and rapid recognition of various targets with high sensitivity and selectivity owing to the novel optical, magnetic, electric, chemical and biological properties of nanomaterials. This paper reviews the latest advances and trends of aptamer-nanomaterial-based optical probes for biomolecules, metal ions and organic compounds, including colorimetry, fluoresence and surface-enhanced Raman spectroscopy (SERS).
研究领域[WOS]: Chemistry
关键词[WOS]: ENHANCED RAMAN-SPECTROSCOPY ; FUNCTIONALIZED GOLD NANOPARTICLES ; FREE COLORIMETRIC DETECTION ; PROTEIN-DETECTION ; QUANTUM-DOT ; MICROFLUIDIC CHANNEL ; THROMBIN DETECTION ; AU NANOPARTICLES ; DNA APTAMER ; SENSOR
文章类型: Article
收录类别: SCI
原文出处: 查看原文
语种: 英语
WOS记录号: WOS:000275994000031
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.yic.ac.cn/handle/133337/3710
Appears in Collections:环境化学实验室_期刊论文

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作者单位: Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China

Recommended Citation:
Wang Guoqing,Chen Zhaopeng,Chen Lingxin. Aptamer-Nanoparticle-Based Optical Probes[J]. PROGRESS IN CHEMISTRY,2010,22(2-3):489-499.
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