Preparation of l-Arginine Schiff Bases Modified Chitosan Derivatives and Their Antimicrobial and Antioxidant Properties | |
Cui, Jingmin1,2,3; Sun, Yan1,2,3; Wang, Linqing4; Miao, Qin1,2,3; Tan, Wenqiang1,3; Guo, Zhanyong1,2,3 | |
发表期刊 | MARINE DRUGS |
2022-11-01 | |
卷号 | 20期号:11页码:16 |
关键词 | chitosan l-arginine Schiff bases heterocyclic compounds |
DOI | 10.3390/md20110688 |
英文摘要 | We successfully prepared a series of l-arginine Schiff bases acylated chitosan derivatives, aiming to improve the antioxidant activity and antimicrobial activity of chitosan by introducing a furan ring, pyridine ring, and l-arginine structure. The accuracy of the structures of ten compounds was characterized by FT-IR and H-1 NMR. In terms of DPPH radical scavenging activity, except for compound CR3PCA, the scavenging rate of other compounds was higher than chitosan, especially CRCF and CRBF had strong scavenging abilities. At the same time, in the superoxide-radical scavenging activity assay, CRCF, CRBF, CR3PCA, CR2C3PCA, and CR2B3PCA were comparable to positive control at 1.60 mg/mL. Simultaneously, CRFF, CRCF, and CRBF had a certain inhibitory effect on Botrytis cinerea. Furthermore, the inhibitory effect of CRFF, CRCF, and CR3PCA on Staphylococcus aureus was very well, close to the positive control at 1.00 mg/mL. CRCF and CR2B3PCA showed better inhibitory effects on Escherichia coli than other compounds. The MTT assay was used to determine the cytotoxicity of the chitosan derivatives, which proved their safety to fibroblast cells. In summary, the study indicated that some of these compounds have the potential for further development and utilization in the preparation of antioxidants and antimicrobial agents. |
收录类别 | SCI |
语种 | 英语 |
关键词[WOS] | AMINO-ACIDS ; ANTIBACTERIAL ; COMPLEXES ; MODE ; COPPER(II) ; PLANT |
研究领域[WOS] | Pharmacology & Pharmacy |
WOS记录号 | WOS:000895550000001 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.yic.ac.cn/handle/133337/31889 |
专题 | 海岸带生物学与生物资源利用重点实验室 海岸带生物学与生物资源利用重点实验室_海岸带生物资源高效利用研究与发展中心 |
通讯作者 | Guo, Zhanyong |
作者单位 | 1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Ctr Oceanmega Sci, Qingdao 266071, Peoples R China 4.Ludong Univ, Sch Chem & Mat Sci, Yantai 264025, Peoples R China |
推荐引用方式 GB/T 7714 | Cui, Jingmin,Sun, Yan,Wang, Linqing,et al. Preparation of l-Arginine Schiff Bases Modified Chitosan Derivatives and Their Antimicrobial and Antioxidant Properties[J]. MARINE DRUGS,2022,20(11):16. |
APA | Cui, Jingmin,Sun, Yan,Wang, Linqing,Miao, Qin,Tan, Wenqiang,&Guo, Zhanyong.(2022).Preparation of l-Arginine Schiff Bases Modified Chitosan Derivatives and Their Antimicrobial and Antioxidant Properties.MARINE DRUGS,20(11),16. |
MLA | Cui, Jingmin,et al."Preparation of l-Arginine Schiff Bases Modified Chitosan Derivatives and Their Antimicrobial and Antioxidant Properties".MARINE DRUGS 20.11(2022):16. |
条目包含的文件 | 条目无相关文件。 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论