Structure elucidation and in vitro rat intestinal fermentation properties of a novel sulfated glucogalactan from Porphyra haitanensis

doi:10.1016/j.fshw.2022.07.062

	Structure elucidation and in vitro rat intestinal fermentation properties of a novel sulfated glucogalactan from Porphyra haitanensis
	Chen, Peilin 1,2; Liu, Lu 2; Cheng, Zirun 2; Zhang, Yi 1,2,3; Zheng, Baodong 1,2,3; Hu, Xiaoke4 ; Zeng, Hongliang 1,2,3
发表期刊	FOOD SCIENCE AND HUMAN WELLNESS
	2023-03-01
卷号	12 期号:2 页码:596-606
关键词	Porphyra haitanensis Structure characterization Fecal microflora Short-chain fatty acids Metabolic function prediction Polysaccharide
DOI	10.1016/j.fshw.2022.07.062
通讯作者	Hu, Xiaoke(xkhu@yic.ac.cn) ; Zeng, Hongliang(zhlfst@fafu.edu.cn)
英文摘要	This study was to investigate the structure and rat fecal microbial fermentation properties of a polysaccharide fraction (PHP2) isolated from the red marine alga Porphyra haitanensis. PHP2 was characterized as a sulfated glucogalactan, with a hypothetical backbone structure of -> 4)G alpha(1 -> 6)G4S beta(1 -> 4)Glc(1 -> and a side chain of Man(1 -> 6)Glc. PHP2 had an irregular spherical chain conformation. The 16S rRNA sequence analysis revealed that PHP2 modulated the rat fecal micro-fl ora composition, with a similar effect to inulin, changing the dominant genus (Lactobacillus and Escherichia-Shigella) and promoting the growth of organisms that degrade sulfur-containing polysaccharides, such as Desulfovibrio, Ruminococcaceae_UCG-005, and Ruminococcus_2. PHP2 can promote production of acetic, propionic and butyric acid by rat fecal micro-flora. Prediction of metabolic function suggested that PHP2 could modulate cholesterol metabolism. The sulfated glucogalactan fermentation behavior may be associated with its monosaccharide composition, chain branching and chain conformation. PHP2 appeared to have considerable potential as functional food, and was associated with sulfur-containing polysaccharides in general. (C) 2023 Beijing Academy of Food Sciences. Publishing services by Elsevier B.V. on behalf of KeAi Communications Co., Ltd.
资助机构	Scientific Research Foundation of Graduate School of Fujian Agriculture and Forestry University ; Program for Leading Talent in Fujian Provincial University
收录类别	SCI
语种	英语
关键词[WOS]	IMMUNOMODULATORY ACTIVITY ; MICROBIAL CATABOLISM ; SIMULATED DIGESTION ; CHAIN CONFORMATION ; KAPPA-CARRAGEENAN ; RESISTANT STARCH ; GUT MICROBIOTA ; POLYSACCHARIDE ; OLIGOSACCHARIDES ; PURIFICATION
研究领域[WOS]	Food Science & Technology ; Nutrition & Dietetics
WOS记录号	WOS:000862039500001
引用统计	被引频次：4[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.yic.ac.cn/handle/133337/31728
专题	海岸带生物学与生物资源利用重点实验室海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室
通讯作者	Hu, Xiaoke; Zeng, Hongliang
作者单位	1.Minist Educ, Engn Res Ctr, Fujian Taiwan Special Marine Food Proc & Nutr, Fuzhou 350002, Peoples R China 2.Fujian Agr & Forestry Univ, Coll Food Sci, Fuzhou 350002, Peoples R China 3.Fujian Agr & Forestry Univ, Fujian Prov Key Lab Qual Sci & Proc Technol Specia, Fuzhou 350002, Peoples R China 4.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China
推荐引用方式 GB/T 7714	Chen, Peilin,Liu, Lu,Cheng, Zirun,et al. Structure elucidation and in vitro rat intestinal fermentation properties of a novel sulfated glucogalactan from Porphyra haitanensis[J]. FOOD SCIENCE AND HUMAN WELLNESS,2023,12(2):596-606.
APA	Chen, Peilin.,Liu, Lu.,Cheng, Zirun.,Zhang, Yi.,Zheng, Baodong.,...&Zeng, Hongliang.(2023).Structure elucidation and in vitro rat intestinal fermentation properties of a novel sulfated glucogalactan from Porphyra haitanensis.FOOD SCIENCE AND HUMAN WELLNESS,12(2),596-606.
MLA	Chen, Peilin,et al."Structure elucidation and in vitro rat intestinal fermentation properties of a novel sulfated glucogalactan from Porphyra haitanensis".FOOD SCIENCE AND HUMAN WELLNESS 12.2(2023):596-606.