Microfluidic paper-based chips in rapid detection: Current status, challenges, and perspectives
Qin, Xiaoxiao1; Liu, Jiajing1; Zhang, Zhong1,2; Li, Jinhua2; Yuan, Li1; Zhang, Zhiyang2; Chen, Lingxin2,3,4
发表期刊TRAC-TRENDS IN ANALYTICAL CHEMISTRY
ISSN0165-9936
2021-10-01
卷号143页码:15
关键词Microfluidic paper-based chips Rapid detection Food safety Portable device Pathogen
DOI10.1016/j.trac.2021.116371
通讯作者Zhang, Zhong() ; Chen, Lingxin(lxchen@yic.ac.cn)
英文摘要Microfluidic paper-based chips (mu PCs) are micro-laboratory analysis systems that use paper instead of traditional microfluidic substrate materials and miniaturize biochemical reactions. Based on traditional 2D mu PCs, the novel mu PCs are innovative 3D structure chips that are realized by fluid channel construction, channel microvalve, folding and other fluid control methods. In recent years, mu PCs have developed rapidly in terms of design and integration and have been widely used in food safety, environmental residue pollution, pathogen detection and other applications. Due to their advantages of low cost, portability and satisfactory thermal stability, they have unique potential in the field of rapid detection. Herein, based on the detailed preparation, we focus on the selection of the paper substrate, microfluidic chip hydrophilic/hydrophobic processing and substrate modification. We highlight the latest research progress of mu PCs in rapid detection from 2014 to 2021, and discuss the remaining challenges and future perspectives for further development. (C) 2021 Elsevier B.V. All rights reserved.
资助机构National Natural Science Foundation of China ; Shaanxi Province Key Research and Development Project ; Postdoctoral Program of Shaanxi Province ; Fundamental Research Fund of the Central University ; Taishan Scholar Project Special Funding
收录类别SCI
语种英语
关键词[WOS]LOW-COST ; FLUORESCENCE DETECTION ; MULTIPLEXED DETECTION ; SENSITIVE DETECTION ; BETA-AGONISTS ; DEVICES ; PLATFORM ; SENSOR ; FABRICATION ; ASSAY
研究领域[WOS]Chemistry
WOS记录号WOS:000729685900011
引用统计
文献类型期刊论文
条目标识符http://ir.yic.ac.cn/handle/133337/31301
专题中国科学院海岸带环境过程与生态修复重点实验室
中国科学院海岸带环境过程与生态修复重点实验室_海岸带环境过程实验室
中国科学院海岸带环境过程与生态修复重点实验室_海岸带环境工程技术研究与发展中心
通讯作者Zhang, Zhong; Chen, Lingxin
作者单位1.Shaanxi Normal Univ, Engn Res Ctr High Value Utilizat Western Fruit Re, Shaanxi Engn Lab Food Green Proc & Safety Control, Coll Food Engn & Nutr Sci,Minist Educ, Xian 710062, Shaanxi, Peoples R China
2.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Shandong Key Lab Coastal Environm Proc, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Shandong, Peoples R China
3.Qufu Normal Univ, Coll Chem & Chem Engn, Qufu 273165, Shandong, Peoples R China
4.Qingdao Univ Technol, Sch Environm & Municipal Engn, Qingdao 266033, Peoples R China
推荐引用方式
GB/T 7714
Qin, Xiaoxiao,Liu, Jiajing,Zhang, Zhong,et al. Microfluidic paper-based chips in rapid detection: Current status, challenges, and perspectives[J]. TRAC-TRENDS IN ANALYTICAL CHEMISTRY,2021,143:15.
APA Qin, Xiaoxiao.,Liu, Jiajing.,Zhang, Zhong.,Li, Jinhua.,Yuan, Li.,...&Chen, Lingxin.(2021).Microfluidic paper-based chips in rapid detection: Current status, challenges, and perspectives.TRAC-TRENDS IN ANALYTICAL CHEMISTRY,143,15.
MLA Qin, Xiaoxiao,et al."Microfluidic paper-based chips in rapid detection: Current status, challenges, and perspectives".TRAC-TRENDS IN ANALYTICAL CHEMISTRY 143(2021):15.
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