Bisabolane, cadinane, and cyclonerane sesquiterpenes from an algicolous strain of Trichoderma asperelloides

doi:10.1016/j.bioorg.2021.105223

	Bisabolane, cadinane, and cyclonerane sesquiterpenes from an algicolous strain of Trichoderma asperelloides
	Zou, Ji-Xue 1,2; Song, Yin-Ping 1; Liu, Xiang-Hong 1,2; Li, Xiao-Nian 3; Ji, Nai-Yun1
发表期刊	BIOORGANIC CHEMISTRY
ISSN	0045-2068
	2021-10-01
卷号	115 页码:9
关键词	Trichoderma Sesquiterpene Bisabolane Cadinane Cyclonerane
DOI	10.1016/j.bioorg.2021.105223
通讯作者	Ji, Nai-Yun(nyji@yic.ac.cn)
英文摘要	Ten new bisabolane derivatives, trichobisabolins Q-Z (1-10), one new cadinane derivative, cadin-4-en-11-ol (11), and three new cyclonerane derivatives, cycloner-3-en-7,11-diol (12), isoepicyclonerodiol oxide (13), and norepicyclonerodiol oxide (14), were isolated from the endophytic fungal strain RR-dl-6-11 of Trichoderma asperelloides that was obtained from a marine alga. Their structures along with relative configurations were established mainly by NMR and IR as well as MS techniques, and the absolute configurations of 10 and 11 were assigned by ECD and X-ray diffraction data, respectively. Sesquiterpenes from the fungus T. asperelloides are reported for the first time. It is interesting that half of the bisabolane derivatives are demethylated. Compound 12 represents the first the occurrence of cyclopentenyl-bearing cycloneranes, and 14 seems a cyclopentyl-degrading cyclonerane derivative. Several isolates feature potent inhibition of marine phytoplankton species.
资助机构	National Natural Science Foundation of China ; Taishan Scholar Project Special Funding
收录类别	SCI
语种	英语
关键词[WOS]	METABOLITES ; HARZIANE
研究领域[WOS]	Biochemistry & Molecular Biology ; Chemistry
WOS记录号	WOS:000704133100007
引用统计	被引频次：8[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.yic.ac.cn/handle/133337/30766
专题	海岸带生物学与生物资源利用重点实验室海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室海岸带生物学与生物资源利用重点实验室_海岸带生物资源高效利用研究与发展中心
通讯作者	Ji, Nai-Yun
作者单位	1.Chinese Acad Sci, Ctr Ocean Megasci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Kunming Inst Bot, Kunming 650201, Yunnan, Peoples R China
推荐引用方式 GB/T 7714	Zou, Ji-Xue,Song, Yin-Ping,Liu, Xiang-Hong,et al. Bisabolane, cadinane, and cyclonerane sesquiterpenes from an algicolous strain of Trichoderma asperelloides[J]. BIOORGANIC CHEMISTRY,2021,115:9.
APA	Zou, Ji-Xue,Song, Yin-Ping,Liu, Xiang-Hong,Li, Xiao-Nian,&Ji, Nai-Yun.(2021).Bisabolane, cadinane, and cyclonerane sesquiterpenes from an algicolous strain of Trichoderma asperelloides.BIOORGANIC CHEMISTRY,115,9.
MLA	Zou, Ji-Xue,et al."Bisabolane, cadinane, and cyclonerane sesquiterpenes from an algicolous strain of Trichoderma asperelloides".BIOORGANIC CHEMISTRY 115(2021):9.