| Cadinane and carotane derivatives from the marine algicolous fungus Trichoderma virens RR-dl-6-8 | |
Song, Yin-Ping1; Ji, Nai-Yun1 ; Shi, Xiao-Shan2; Wang, Bin-Gui2
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| 发表期刊 | FITOTERAPIA
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| ISSN | 0367-326X |
| 2020-10 | |
| 卷号 | 146页码:104715 |
| 关键词 | Trichoderma virens Sesquiterpene Cadinane Carotane |
| DOI | 10.1016/j.fitote.2020.104715 |
| 英文摘要 | Eight cadinane derivatives, trichocadinins H - N (1-7) and methylhydroheptelidate (8), and two carotane derivatives, 14-O-methyltrichocarotin G (9) and 14-O-methyl CAF-603 (10), including eight new ones (1-6, 9, and 10), were isolated from the culture of Trichoderma virens RR-dl-6-8 obtained from the organohalogen-enriched marine red alga Rhodomela confervoides. Their structures and relative configurations were established by analysis of NMR and mass spectroscopic data, and the absolute configurations were assigned on the basis of ECD curves, highlighted by the ECD diversity of carboxylic acid derivatives. Among the isolates, 1 with a halogen atom and 8, a new naturally occurring compound, are 2,3-seco-cadinane sesquiterpenes, and the epimeric 2 and 3 feature a 2-nor-cadinane skeleton. A commercially-sourced compound with the same planar structure as that of 7 has been reported in a patent, but its configuration was not given. Compounds 1-10 exhibited growth inhibition of some marine phytoplankton species. |
| 资助机构 | Natural Science Foundation for Distinguished Young Scholars of Shandong Province [JQ201712] ; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31670355] ; Youth Innovation Promotion Association of the CAS [Y201734] ; Shuangbai Plan of Yantai [2018-3] ; Taishan Scholar Project Special Funding [tsqn201909164] |
| 收录类别 | SCI |
| 语种 | 英语 |
| 关键词[WOS] | SECONDARY METABOLITES |
| 研究领域[WOS] | Pharmacology & Pharmacy |
| WOS记录号 | WOS:000580427700061 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.yic.ac.cn/handle/133337/30494 |
| 专题 | 海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室 |
| 作者单位 | 1.Chinese Acad Sci, Ctr Ocean Megasci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China; 2.Chinese Acad Sci, Ctr Ocean Megasci, Inst Oceanol,Key Lab Expt Marine Biol, Lab Marine Biol & Biotechnol,Qingdao Natl Lab Mar, Qingdao 266071, Peoples R China |
| 推荐引用方式 GB/T 7714 | Song, Yin-Ping,Ji, Nai-Yun,Shi, Xiao-Shan,et al. Cadinane and carotane derivatives from the marine algicolous fungus Trichoderma virens RR-dl-6-8[J]. FITOTERAPIA,2020,146:104715. |
| APA | Song, Yin-Ping,Ji, Nai-Yun,Shi, Xiao-Shan,&Wang, Bin-Gui.(2020).Cadinane and carotane derivatives from the marine algicolous fungus Trichoderma virens RR-dl-6-8.FITOTERAPIA,146,104715. |
| MLA | Song, Yin-Ping,et al."Cadinane and carotane derivatives from the marine algicolous fungus Trichoderma virens RR-dl-6-8".FITOTERAPIA 146(2020):104715. |
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| Cadinane and carotan（2128KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | 浏览 请求全文 | |
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