The gut microbiota and its products: Establishing causal relationships with obesity related outcomes
Li, Lili1,2; Zhang, Yubing1,3; Speakman, John Roger4; Hu, Shanliang5; Song, Yipeng5; Qin, Song1,2
发表期刊OBESITY REVIEWS
ISSN1467-7881
2021-09-06
页码14
关键词causality gut microbiota metabolites obesity
DOI10.1111/obr.13341
通讯作者Song, Yipeng(syp1972@sina.com) ; Qin, Song(sqin@yic.ac.cn)
英文摘要Gut microorganisms not only participate in the metabolism of carbohydrate, lipids, protein, and polypeptides in the intestine but also directly affect the metabolic phenotypes of the host. Although many studies have described the apparent effects of gut microbiota on human health, the development of metagenomics and culturomics in the past decade has generated a large amount of evidence suggesting a causal relationship between gut microbiota and obesity. The interaction between the gut microbiota and host is realized by microbial metabolites with multiple biological functions. We concentrated here on several representative beneficial species connected with obesity as well as the mechanisms, with particular emphasis on microbiota-dependent metabolites. Finally, we consider the potential clinical significance of these relationships to fuel the conception and realization of novel therapeutic and preventive strategies.
资助机构Science and Technology Program of Yantai ; Youth Innovation Promotion Association of the Chinese Academy of Sciences
收录类别SCI
语种英语
关键词[WOS]VISCERAL FAT ACCUMULATION ; DIET-INDUCED OBESITY ; CHAIN AMINO-ACIDS ; LACTIS CECT 8145 ; BODY-MASS INDEX ; INSULIN-RESISTANCE ; BIFIDOBACTERIUM-ANIMALIS ; LACTOBACILLUS-REUTERI ; AKKERMANSIA-MUCINIPHILA ; INTESTINAL MICROBIOTA
研究领域[WOS]Endocrinology & Metabolism
WOS记录号WOS:000693844400001
引用统计
被引频次:13[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.yic.ac.cn/handle/133337/29747
专题海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室
通讯作者Song, Yipeng; Qin, Song
作者单位1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai, Peoples R China
2.Yantai Univ, Coll Life Sci, Yantai, Peoples R China
3.Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao, Peoples R China
4.Chinese Acad Sci, Shenzhen Inst Adv Technol, Ctr Energy Metab & Reprod, Shenzhen Key Lab Metab Hlth, Shenzhen, Peoples R China
5.Yantai Yuhuangding Hosp, Dept Radiotherapy, Yantai, Peoples R China
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GB/T 7714
Li, Lili,Zhang, Yubing,Speakman, John Roger,et al. The gut microbiota and its products: Establishing causal relationships with obesity related outcomes[J]. OBESITY REVIEWS,2021:14.
APA Li, Lili,Zhang, Yubing,Speakman, John Roger,Hu, Shanliang,Song, Yipeng,&Qin, Song.(2021).The gut microbiota and its products: Establishing causal relationships with obesity related outcomes.OBESITY REVIEWS,14.
MLA Li, Lili,et al."The gut microbiota and its products: Establishing causal relationships with obesity related outcomes".OBESITY REVIEWS (2021):14.
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