Antifungal activity of double Schiff bases of chitosan derivatives bearing active halogeno-benzenes

doi:10.1016/j.ijbiomac.2021.02.184

	Antifungal activity of double Schiff bases of chitosan derivatives bearing active halogeno-benzenes
	Wei, Lijie 1,2,3; Zhang, Jingjing 1,2; Tan, Wenqiang1,2 ; Wang, Gang1,2 ; Li, Qing1,2 ; Dong, Fang1,2 ; Guo, Zhanyong1,2,4
发表期刊	INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
ISSN	0141-8130
	2021-05-15
卷号	179 页码:292-298
关键词	Antifungal activity Chitosan derivatives Schiff base
DOI	10.1016/j.ijbiomac.2021.02.184
通讯作者	Zhang, Jingjing(jingjingzhang@yic.ac.cn) ; Guo, Zhanyong(zhanyongguo@hotmail.com)
英文摘要	In this study, a series of chitosan derivatives bearing active halogenated aromatic imines were successfully synthesized via Schiff bases with the high degrees of substitution. Detailed structural characterization was carried out using Fourier transform infrared (FTIR) spectroscopy, solid-state C-13 nuclear magnetic resonance (NMR) spectroscopy, and elemental analysis. Besides, the antifungal activity against three common plant pathogenic fungi, including Botrytis cinerea, Fusarium oxysporum f. sp. cucumerinum, and Fusarium oxysporum f. sp. niveum, was investigated using in vitro hyphal measurements. The results showed that double Schiff bases of chitosan derivatives exhibited enhanced antifungal activity compared with chitosan, especially at 1.0 mg/mL. The double Schiff bases of chitosan bearing halogeno-benzenes showed >95% inhibitory indices at 1.0 mg/mL against Botrytis cinereal since halogens had the stronger electron-withdrawing property. The higher degree of substitution was another positive effect to improve the antifungal activity. This study provides a practical strategy to synthesize new double Schiff bases of chitosan derivatives bearing halogeno-benzenes, which could be developed into stronger antifungal agents. (C) 2021 Elsevier B.V. All rights reserved.
资助机构	Youth Innovation Promotion Association CAS ; Natural Science Foundation of Shandong Province of China ; National Key Research and Development Program of China ; Natural Science Foundation of Shandong Province Science and Technology Development Plan
收录类别	SCI
语种	英语
关键词[WOS]	ANTIMICROBIAL ACTIVITY ; ANTIBACTERIAL ACTIVITY ; BIOLOGICAL-ACTIVITY ; INULIN DERIVATIVES ; ANTIOXIDANT ; FILMS
研究领域[WOS]	Biochemistry & Molecular Biology ; Chemistry ; Polymer Science
WOS记录号	WOS:000645619000008
引用统计	被引频次：38[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.yic.ac.cn/handle/133337/29334
专题	海岸带生物学与生物资源利用重点实验室海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室中国科学院海岸带环境过程与生态修复重点实验室_海岸带环境过程实验室海岸带生物学与生物资源利用重点实验室_海岸带生物资源高效利用研究与发展中心
通讯作者	Zhang, Jingjing; Guo, Zhanyong
作者单位	1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China 2.Chinese Acad Sci, Ctr Ocean Megasci, 7 Nanhai Rd, Qingdao 266071, Peoples R China 3.Weifang Inspect & Testing Ctr, Weifang 261000, Shandong, Peoples R China 4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Wei, Lijie,Zhang, Jingjing,Tan, Wenqiang,et al. Antifungal activity of double Schiff bases of chitosan derivatives bearing active halogeno-benzenes[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2021,179:292-298.
APA	Wei, Lijie.,Zhang, Jingjing.,Tan, Wenqiang.,Wang, Gang.,Li, Qing.,...&Guo, Zhanyong.(2021).Antifungal activity of double Schiff bases of chitosan derivatives bearing active halogeno-benzenes.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,179,292-298.
MLA	Wei, Lijie,et al."Antifungal activity of double Schiff bases of chitosan derivatives bearing active halogeno-benzenes".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 179(2021):292-298.

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