Integrative phenotypic and gene expression data identify myostatin as a muscle growth inhibitor in chinese shrimp Fenneropenaeus chinensis | |
Jie Kong; Yunjun Yan; Xia Lu; Sheng Luan; Xianhong Meng; Ping Dai; Baolong chen; Baoxiang cao; Guangfeng Qiang; Kun Luo | |
发表期刊 | Scientific Reports |
2020 | |
卷号 | 10页码:5985 |
DOI | https://doi.org/10.1038/s41598-020-61382-8 |
英文摘要 | Growth traits, largely determined by muscle growth, are the most critical economic traits in shrimp breeding. Myostatin (Mstn) is a conserved inhibitor of muscle growth in vertebrates, but until now solid evidence supporting a similar function of Mstn in invertebrates has been lacking. In the present study, we examined the Mstn expression along with growth trait data in a Fenneropenaeus chinensis population, to establish a potential correlation between Mstn and growth. The heritabilities of FcMstn expression, body weight at 190 days of culture, body weight and length at 230 days of culture, and average daily gain were estimated using 773 individuals and a thirteen-generation pedigree. The results showed FcMstn expression was negatively correlated with the growth traits, and the mean FcMstn expression in females was significantly lower than that of males, indicating Mstn negatively regulates muscle growth in shrimp, and its lower expression may underscore the faster growth of females. Low heritabilities were detected for FcMstn expression, suggesting that the expression of Mstn might be heritable in shrimp. These results provide strong support for a growth inhibitory function of Mstn in F. chinensis, and suggest a potential method for selective breeding of this species without substantial experimental resources and labor force. |
收录类别 | SCI |
语种 | 英语 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.yic.ac.cn/handle/133337/25253 |
专题 | 个人在本单位外知识产出 |
通讯作者 | Xia Lu |
推荐引用方式 GB/T 7714 | Jie Kong,Yunjun Yan,Xia Lu,et al. Integrative phenotypic and gene expression data identify myostatin as a muscle growth inhibitor in chinese shrimp Fenneropenaeus chinensis[J]. Scientific Reports,2020,10:5985. |
APA | Jie Kong.,Yunjun Yan.,Xia Lu.,Sheng Luan.,Xianhong Meng.,...&Kun Luo.(2020).Integrative phenotypic and gene expression data identify myostatin as a muscle growth inhibitor in chinese shrimp Fenneropenaeus chinensis.Scientific Reports,10,5985. |
MLA | Jie Kong,et al."Integrative phenotypic and gene expression data identify myostatin as a muscle growth inhibitor in chinese shrimp Fenneropenaeus chinensis".Scientific Reports 10(2020):5985. |
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