| Synthesis, characterization, and the antioxidant activity of the acetylated chitosan derivatives containing sulfonium salts | |
Sun, Xueqi; Zhang, Jingjing; Mi, Yingqi; Chen, Yuan; Tan, Wenqiang; Li, Qing ; Dong, Fang; Guo, Zhanyong
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| Source Publication | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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| 2020-06-01 | |
| Volume | 152Pages:349-358 |
| Keyword | STARCH DERIVATIVES LIGANDS SYNTHESIS THIOETHER ANTIFUNGAL COMPLEXES |
| MOST Discipline Catalogue | Biochemistry & Molecular Biology ; Chemistry, Applied ; Polymer Science |
| DOI | 10.1016/j.ijbiomac.2020.02.177 |
| Contribution Rank | [Sun, Xueqi; Zhang, Jingjing; Mi, Yingqi; Chen, Yuan; Tan, Wenqiang; Li, Qing; Dong, Fang; Guo, Zhanyong] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China; [Sun, Xueqi; Zhang, Jingjing; Mi, Yingqi; Chen, Yuan; Tan, Wenqiang; Li, Qing; Dong, Fang; Guo, Zhanyong] Chinese Acad Sci, Ctr Ocean Megasci, 7 Nanhai Rd, Qingdao 266071, Peoples R China; [Sun, Xueqi; Zhang, Jingjing; Mi, Yingqi; Chen, Yuan; Guo, Zhanyong] Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| Department | 海岸带生物资源高效利用研究与发展中心 |
| Abstract | In this study, a new class of chitosan derivatives possessing sulfonium salts was synthesized, and characterized by H-1 NMR, C-13 NMR, and elemental analyses. IR spectra, H-1 NMR and C-13 NMR of the structural units of these polymers validated the designed chitosan derivatives were successfully synthesized. In addition, the antioxidant potential of chitosan and chitosan derivatives was assessed in vitro, screened by 2,2-diphenyl-l-picrylhydrazyl (DPPH) free radical scavenging, hydroxyl radical scavenging, and superoxide radical scavenging, respectively. Results revealed that designed chitosan derivatives could effectively scavenge DPPH radical, hydroxyl radical, and superoxide radical with inhibition rate of more than 90% at 1.6 mg/mL, higher than chitosan. Moreover, in the cytotoxicity assay, no cytotoxicity was observed for the 1929 cells with chitosan and its derivatives at all the testing concentrations. These results indicated that the acetylated chitosan derivatives containing sulfonium salts may be a promising natural antioxidant for the pharmaceutics, food, cosmetics and agriculture management. (C) 2020 Elsevier B.V. All rights reserved. |
| Subtype | Article |
| Indexed By | SCI |
| Language | 英语 |
| WOS Keyword | STARCH DERIVATIVES ; LIGANDS SYNTHESIS ; THIOETHER ; ANTIFUNGAL ; COMPLEXES |
| WOS ID | WOS:000530068000036 |
| Funding Organization | National Key Research and Development Program of China [2019YFD0900705] ; Natural Science Foundation of Shandong Province of ChinaNatural Science Foundation of Shandong Province [ZR2019BD064, ZR2017BD015] ; Youth Innovation Promotion Association CAS [2020219] ; National Natural Science Foundation of ChinaNational Natural Science Foundation of China [41576156] ; Natural Science Foundation of Shandong Province Science and Technology Development Plan [2019GHY112010] |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.yic.ac.cn/handle/133337/25022 |
| Collection | 海岸带生物学与生物资源利用重点实验室_海岸带生物资源高效利用研究与发展中心 |
| Affiliation | 1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China; 2.Chinese Acad Sci, Ctr Ocean Megasci, 7 Nanhai Rd, Qingdao 266071, Peoples R China; 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| Recommended Citation GB/T 7714 | Sun, Xueqi,Zhang, Jingjing,Mi, Yingqi,et al. Synthesis, characterization, and the antioxidant activity of the acetylated chitosan derivatives containing sulfonium salts[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2020,152:349-358. |
| APA | Sun, Xueqi.,Zhang, Jingjing.,Mi, Yingqi.,Chen, Yuan.,Tan, Wenqiang.,...&Guo, Zhanyong.(2020).Synthesis, characterization, and the antioxidant activity of the acetylated chitosan derivatives containing sulfonium salts.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,152,349-358. |
| MLA | Sun, Xueqi,et al."Synthesis, characterization, and the antioxidant activity of the acetylated chitosan derivatives containing sulfonium salts".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 152(2020):349-358. |
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| Synthesis, character（1569KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | View Download | |
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