| Synthesis, Characterization, and Antifungal Activity of Schiff Bases of Inulin Bearing Pyridine ring | |
Wei, LJ; Tan, WQ ; Zhang, JJ; Mi, YQ; Dong, F; Li, Q; Guo, ZY
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| 发表期刊 | POLYMERS
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| 2019-02 | |
| 卷号 | 11期号:2页码:371 |
| 关键词 | inulin Schiff base antifungal |
| 研究领域 | Polymer Science |
| DOI | 10.3390/polym11020371 |
| 产权排序 | [Wei, Lijie; Tan, Wenqiang; Zhang, Jingjing; Mi, Yingqi; Dong, Fang; Li, Qing; Guo, Zhanyong] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China; [Wei, Lijie; Zhang, Jingjing; Mi, Yingqi; Guo, Zhanyong] Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 作者部门 | 海岸带生物资源高效利用研究与发展中心 |
| 英文摘要 | As a renewable, biocompatible, and biodegradable polysaccharide, inulin has a good solubility in water and some physiological functions. Chemical modification is one of the important methods to improve the bioactivity of inulin. In this paper, based on 6-amino-6-deoxy-3,4-acetyl inulin (3), three kinds of Schiff bases of inulin bearing pyridine rings were successfully designed and synthesized. Detailed structural characterization was carried out using FTIR, C-13 NMR, and H-1 NMR spectroscopy, and elemental analysis. Moreover, the antifungal activity of Schiff bases of inulin against three plant pathogenic fungi, including Botrytis cinerea, Fusarium oxysporum f.sp.niveum, and Phomopsis asparagi, were evaluated using in vitro hypha measurements. Inulin, as a natural polysaccharide, did not possess any antifungal activity at the tested concentration against the targeted fungi. Compared with inulin and the intermediate product 6-amino-6-deoxy-3,4-acetyl inulin (3), all the synthesized Schiff bases of inulin derivatives with >54.0% inhibitory index at 2.0 mg/mL exhibited enhanced antifungal activity. 3NS, with an inhibitory index of 77.0% exhibited good antifungal activity against Botrytis cinerea at 2.0 mg/mL. The synthesized Schiff bases of inulin bearing pyridine rings can be prepared for novel antifungal agents to expand the application of inulin. |
| 文章类型 | Article |
| 资助机构 | National Natural Science Foundation of ChinaNational Natural Science Foundation of China [41576156] ; seed project of Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences [YIC Y755031011] ; Natural Science Foundation of Shandong Province of ChinaNatural Science Foundation of Shandong Province [ZR 2017BD015] ; Science and Technology Service Network Initiative of Chinese Academy of sciences [KFJ-STSZDTP-023] |
| 收录类别 | SCI |
| 语种 | 英语 |
| 关键词[WOS] | CHITOSAN DERIVATIVES ; ANTIOXIDANT ACTIVITY ; ANTIBACTERIAL |
| 研究领域[WOS] | Polymer Science |
| WOS记录号 | WOS:000460296000185 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.yic.ac.cn/handle/133337/25004 |
| 专题 | 海岸带生物学与生物资源利用重点实验室_海岸带生物资源高效利用研究与发展中心 海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室 中国科学院海岸带环境过程与生态修复重点实验室_污染过程与控制实验室 |
| 作者单位 | 1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China; 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wei, LJ,Tan, WQ,Zhang, JJ,et al. Synthesis, Characterization, and Antifungal Activity of Schiff Bases of Inulin Bearing Pyridine ring[J]. POLYMERS,2019,11(2):371. |
| APA | Wei, LJ.,Tan, WQ.,Zhang, JJ.,Mi, YQ.,Dong, F.,...&Guo, ZY.(2019).Synthesis, Characterization, and Antifungal Activity of Schiff Bases of Inulin Bearing Pyridine ring.POLYMERS,11(2),371. |
| MLA | Wei, LJ,et al."Synthesis, Characterization, and Antifungal Activity of Schiff Bases of Inulin Bearing Pyridine ring".POLYMERS 11.2(2019):371. |
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| Synthesis, Character（1977KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | 浏览 请求全文 | |
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