| Facile synthesis of zirconia-coated mesoporous silica particles by hydrothermal strategy under low potential of hydrogen conditions and functionalization with dodecylphosphonic acid for high-performance liquid chromatography | |
Song, ZH; Li, SH; Guan, YF; Wang, S; Wang, YH; Yang, GQ; Zhang, XC; Li, JH ; Song, WH; Zhou, CM; Chen, LX
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| 发表期刊 | JOURNAL OF CHROMATOGRAPHY A
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| ISSN | 0021-9673 |
| 2020-02-08 | |
| 卷号 | 1612页码:460659 |
| 关键词 | ZrO2/SiO2-n synthesis Dodecylphosphonic acid Hydrophilic interaction chromatography (HILIC) Reversed-phase liquid chromatography (RPLC) |
| 研究领域 | Biochemical Research Methods ; Chemistry, Analytical |
| DOI | 10.1016/j.chroma.2019.460659 |
| 产权排序 | [Song, Zhihua; Wang, Yinghao; Yang, Gangqiang; Zhang, Xiaochen; Song, Wenhao; Zhou, Chuanming] Yantai Univ, Collaborat Innovat Ctr Adv Drug Delivery Syst & B, Key Lab Mol Pharmacol & Drug Evaluat, Sch Pharm,Minist Educ, Yantai 264005, Peoples R China; [Li, Shenghong; Guan, Yafeng; Wang, Shuo] Chinese Acad Sci, Dalian Inst Chem Phys, CAS Key Lab Separat Sci Analyt Chem, 457 Zhongshan Rd, Dalian 116023, Peoples R China; [Li, Jinhua; Chen, Lingxin] Chinese Acad Sci, Res Ctr Coastal Environm Engn & Technol, Yantai Inst Coastal Zone Res, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China |
| 通讯作者 | Song, Zhihua(zhihuasong08@yeah.net) |
| 作者部门 | 海岸带环境工程技术研究与发展中心 |
| 英文摘要 | In this work, multilayer zirconia-coated silica (ZrO2/SiO2-n) microspheres were successfully produced by a straightforward hydrothermal procedure with a low concentration of Zr4+ (5 mM) under low potential of hydrogen (pH) conditions (pH = = 2). The obtained ZrO2/SiO2-n materials exhibited favorable characteristics for high-performance liquid chromatography (HPLC) separation, including high surface area and pore volume, good pore structure, narrow particle size, and pore size distribution. In addition, the zirconia coverage in the mesopores was confirmed by soaking the material in 1 M NaOH solution, with the particles showing strong resistance to the basic solution. The obtained ZrO2/SiO2-n stationary phases were packed into a fused-silica capillary tubing for the separation of alkaloids in hydrophilic interaction chromatography (HILIC) mode, and a column efficiency of 47,800 plates/m was obtained for berberine on a ZrO2/SiO2-6 micro column. The ZrO2/SiO2-6 microspheres were further modified by dodecylphosphonic acid (C12P-2-ZrO2/SiO2-6); the C12P-2-ZrO2/SiO2-6 material showed great potential for application in reversed-phase liquid chromatography (RPLC) mode. The C12P-2-ZrO2/SiO2-6 micro column showed a column efficiency of 55,000 plates/m for naphthalene and 51,300 plates/m for benzene. (C) 2019 Elsevier B.V. All rights reserved. |
| 文章类型 | Article |
| 资助机构 | Foundation of Laboratory in Yantai university of P. R China [21575159] ; National Natural Science Foundation of P. R ChinaNational Natural Science Foundation of China [21575159] ; Department of Science and Technology of Shandong Province of China [GG201709290055] ; Taishan Scholar Project Special Funding |
| 收录类别 | SCI |
| 语种 | 英语 |
| 关键词[WOS] | PACKED CAPILLARY COLUMNS ; STATIONARY-PHASE ; NANOPARTICLES ; TITANIA ; ALUMINA ; METHODOLOGY ; NANOSHELLS ; SPHERES |
| 研究领域[WOS] | Biochemical Research Methods ; Chemistry, Analytical |
| WOS记录号 | WOS:000514749200024 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.yic.ac.cn/handle/133337/24753 |
| 专题 | 中国科学院海岸带环境过程与生态修复重点实验室_海岸带环境工程技术研究与发展中心 中国科学院海岸带环境过程与生态修复重点实验室 |
| 作者单位 | 1.Yantai Univ, Collaborat Innovat Ctr Adv Drug Delivery Syst & B, Key Lab Mol Pharmacol & Drug Evaluat, Sch Pharm,Minist Educ, Yantai 264005, Peoples R China; 2.Chinese Acad Sci, Dalian Inst Chem Phys, CAS Key Lab Separat Sci Analyt Chem, 457 Zhongshan Rd, Dalian 116023, Peoples R China; 3.Chinese Acad Sci, Res Ctr Coastal Environm Engn & Technol, Yantai Inst Coastal Zone Res, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China |
| 推荐引用方式 GB/T 7714 | Song, ZH,Li, SH,Guan, YF,et al. Facile synthesis of zirconia-coated mesoporous silica particles by hydrothermal strategy under low potential of hydrogen conditions and functionalization with dodecylphosphonic acid for high-performance liquid chromatography[J]. JOURNAL OF CHROMATOGRAPHY A,2020,1612:460659. |
| APA | Song, ZH.,Li, SH.,Guan, YF.,Wang, S.,Wang, YH.,...&Chen, LX.(2020).Facile synthesis of zirconia-coated mesoporous silica particles by hydrothermal strategy under low potential of hydrogen conditions and functionalization with dodecylphosphonic acid for high-performance liquid chromatography.JOURNAL OF CHROMATOGRAPHY A,1612,460659. |
| MLA | Song, ZH,et al."Facile synthesis of zirconia-coated mesoporous silica particles by hydrothermal strategy under low potential of hydrogen conditions and functionalization with dodecylphosphonic acid for high-performance liquid chromatography".JOURNAL OF CHROMATOGRAPHY A 1612(2020):460659. |
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