| Synthesis of Novel Amino Lactose and Evaluation of Its Antioxidant Property | |
Li, Qing ; Feng, Yan; Gu, Guodong; Guo, Zhanyong
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| 发表期刊 | STARCH-STARKE
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| ISSN | 0038-9056 |
| 2018-05 | |
| 卷号 | 70期号:5-6页码:1700293 |
| 关键词 | amino lactose antioxidant activity chemical modifications |
| 研究领域 | Food Science & Technology |
| DOI | 10.1002/star.201700293 |
| 产权排序 | [Li, Qing; Feng, Yan; Guo, Zhanyong] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China; [Feng, Yan; Guo, Zhanyong] Univ Chinese Acad Sci, Beijing 100049, Peoples R China; [Gu, Guodong] Alliance Pharma Inc, 17 Lee Blvd Malvern, Malvern, PA 19355 USA |
| 作者部门 | 海岸带生物资源高效利用研究与发展中心 |
| 英文摘要 | In order to improve the bioactivity of lactose, a novel lactose derivative is designed and synthesized by introducing an amino group to the C-6 of lactose. The in vitro antioxidant activities of synthesized lactose derivatives are assessed. It shows better scavenging activity against hydrogen peroxide (IC50<0.1mgmL(-1)), hydroxyl radicals (IC50 0.55mgmL(-1)), and DPPH radicals (IC50 0.37mgmL(-1)) than lactose. Based on this data, it is reasonable to propose that the introduction of amino group through chemical modification is significant to enhance the free antioxidant activity of lactose. This derivatization strategy might provide an effective tool to broaden utilization of lactose. |
| 文章类型 | Article |
| 资助机构 | Yantai Science and Technology Development Plan [2015ZH078] ; Public Science and Technology Research Funds Projects of Ocean [201505022-3] ; Natural Science Foundation of Shandong Province of China [ZR2017BD015] ; National Natural Science Foundation of China [41576156] |
| 收录类别 | SCI |
| 语种 | 英语 |
| 关键词[WOS] | ANTIFUNGAL ACTIVITY ; CHITOSAN DERIVATIVES ; INULIN DERIVATIVES ; DRUG-RELEASE ; STARCH ; FILMS ; POLYSACCHARIDE ; AMYLASE ; DESIGN ; IMPACT |
| 研究领域[WOS] | Food Science & Technology |
| WOS记录号 | WOS:000431735200022 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.yic.ac.cn/handle/133337/24477 |
| 专题 | 海岸带生物学与生物资源利用重点实验室_海岸带生物资源高效利用研究与发展中心 海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室 |
| 作者单位 | 1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China; 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China; 3.Alliance Pharma Inc, 17 Lee Blvd Malvern, Malvern, PA 19355 USA |
| 推荐引用方式 GB/T 7714 | Li, Qing,Feng, Yan,Gu, Guodong,et al. Synthesis of Novel Amino Lactose and Evaluation of Its Antioxidant Property[J]. STARCH-STARKE,2018,70(5-6):1700293. |
| APA | Li, Qing,Feng, Yan,Gu, Guodong,&Guo, Zhanyong.(2018).Synthesis of Novel Amino Lactose and Evaluation of Its Antioxidant Property.STARCH-STARKE,70(5-6),1700293. |
| MLA | Li, Qing,et al."Synthesis of Novel Amino Lactose and Evaluation of Its Antioxidant Property".STARCH-STARKE 70.5-6(2018):1700293. |
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| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
| Synthesis of Novel A（798KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | 浏览 请求全文 | |
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