| Synthesis, characterization, and the antifungal activity of chitosan derivatives containing urea groups | |
Zhang, Jingjing; Tan, Wenqiang ; Zhang, Zhenpeng; Song, Yinping; Li, Qing; Dong, Fang; Guo, Zhanyong
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| Source Publication | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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| ISSN | 0141-8130 |
| 2018-04 | |
| Volume | 109Pages:1061-1067 |
| Keyword | Antifungal activity Beneficial soil microbes Chitosan derivatives Structure characteristics Urea groups |
| MOST Discipline Catalogue | Biochemistry & Molecular Biology ; Chemistry, Applied ; Polymer Science |
| DOI | 10.1016/j.ijbiomac.2017.11.092 |
| Contribution Rank | [Zhang, Jingjing; Tan, Wenqiang; Zhang, Zhenpeng; Song, Yinping; Li, Qing; Dong, Fang; Guo, Zhanyong] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China; [Zhang, Jingjing; Tan, Wenqiang; Zhang, Zhenpeng; Song, Yinping; Guo, Zhanyong] Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| Department | 海岸带生物资源高效利用研究与发展中心 |
| Abstract | As an abundant and renewable polysaccharide, chitosan has been drawing broad attention due to its natural properties. For the further utilization of chitosan, chemical modification can be applied in improving its water solubility and the bioactivities. In this study, four chitosan derivatives were synthesized by the reaction of chloracetyl chitosan derivative with quaternary ammonium salt (CTCS) and urea groups bearing 4-amino-pyridine, including BCTCS, 2CBCTCS, 3CBCTCS, and 4CBCTCS. The structure characteristics of synthesized products were established based on FT-1R spectroscopy, H-1 NMR, and elemental analysis. Their antifungal activities against Fusarium oxysporum f. sp. niveum, Phomopsis asparagus, Fusarium oxysporum f. sp. cucumebrium Owen, and Botrytis cinerea were estimated by hyphal measurement in vitro. Generally, the inhibition ratio of most products was higher than 80% at 1.0 mg/mL. Their inhibitory activity decreased roughly in the order: 4CBCTCS > 3CBCTCS > 2CBCTCS> BCTCS > CTCS> chitosan, resulted from the different degrees of substitution of the effectively active groups-urea groups. Meanwhile, the effects on beneficial soil microbes, including Bacillus cereus, Bacillus subtilis, and Sinorhizobium saheli LMG7837, of these synthesized chitosan derivatives were evaluated by disk diffusion method. The results showed that these substances do not inhibit the growth of beneficial bacteria and some of them could be employed as green antifungal biomaterials. (C) 2017 Elsevier B.V. All rights reserved. |
| Subtype | Article |
| Funding Organization | National Natural Science Foundation of China [41576156] ; Shandong Province Science and Technology Development Plan [2015GSF121045] ; Yantai Science and Technology Development Plan [2015ZH078] ; Technology Research Funds Projects of Ocean [2015418022-3] |
| Indexed By | SCI |
| Language | 英语 |
| WOS Keyword | FUNCTIONALIZED CHITOSAN ; ANTIBACTERIAL ACTIVITY ; ANTIOXIDANT ACTIVITIES ; QUATERNIZED CHITOSAN ; INULIN DERIVATIVES ; FACILE SYNTHESIS ; IN-SILICO ; AGENTS ; COMPLEXES ; CONJUGATION |
| WOS Research Area | Biochemistry & Molecular Biology ; Chemistry ; Polymer Science |
| WOS ID | WOS:000428099900115 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.yic.ac.cn/handle/133337/24379 |
| Collection | 海岸带生物学与生物资源利用重点实验室_海岸带生物资源高效利用研究与发展中心 海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室 中科院海岸带环境过程与生态修复重点实验室_污染过程与控制实验室 |
| Affiliation | 1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China; 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| Recommended Citation GB/T 7714 | Zhang, Jingjing,Tan, Wenqiang,Zhang, Zhenpeng,et al. Synthesis, characterization, and the antifungal activity of chitosan derivatives containing urea groups[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2018,109:1061-1067. |
| APA | Zhang, Jingjing.,Tan, Wenqiang.,Zhang, Zhenpeng.,Song, Yinping.,Li, Qing.,...&Guo, Zhanyong.(2018).Synthesis, characterization, and the antifungal activity of chitosan derivatives containing urea groups.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,109,1061-1067. |
| MLA | Zhang, Jingjing,et al."Synthesis, characterization, and the antifungal activity of chitosan derivatives containing urea groups".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 109(2018):1061-1067. |
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