Polyamine-Targeting Gefitinib Prodrug and its Near-Infrared Fluorescent Theranostic Derivative for Monitoring Drug Delivery and Lung Cancer Therapy

doi:10.7150/thno.24041

	Polyamine-Targeting Gefitinib Prodrug and its Near-Infrared Fluorescent Theranostic Derivative for Monitoring Drug Delivery and Lung Cancer Therapy
	Song, Xinyu 1,2; Han, Xiaoyue 2,4; Yu, Fabiao 2,3; Zhang, Xiaoyu 1,2; Chen, Lingxin2,3 ; Lv, Changjun 1,3
发表期刊	THERANOSTICS
ISSN	1838-7640
	2018
卷号	8 期号:8 页码:2217-2228
关键词	Lung Cancer Drug Delivery Targeting Prodrug Fluorescence Theranostics Precision Medicine
研究领域	Medicine, Research & Experimental
DOI	10.7150/thno.24041
产权排序	[Song, Xinyu; Zhang, Xiaoyu; Lv, Changjun] Binzhou Med Univ Hosp, Dept Resp Med, Binzhou 256603, Peoples R China; [Song, Xinyu; Han, Xiaoyue; Yu, Fabiao; Zhang, Xiaoyu; Chen, Lingxin] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China; [Yu, Fabiao; Chen, Lingxin; Lv, Changjun] Binzhou Med Univ, Inst Mol Med, Med Res Ctr, Yantai 264003, Peoples R China; [Han, Xiaoyue] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
作者部门	海岸带环境工程技术研究与发展中心
英文摘要	The therapy of non-small-cell lung cancer (NSCLC) is challenging because of poor prognosis. There are urgent demands for targeting anti-tumor drugs with reliable efficacy and clear pharmacokinetics.
文章类型	Article
资助机构	National Nature Science Foundation of China(21775162, 31470415, 81670064, 21575159, 41776110) ; program of Youth Innovation Promotion Association, CAS(2015170) ; Medical Science and Technology Development Project of Shandong Province(2017WS800) ; State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, CAS(KF2016-22) ; Instrument Developing Project of the Chinese Academy of Sciences(YZ201662)
收录类别	SCI
语种	英语
关键词[WOS]	IN-VIVO ; MOLECULES ; PROBE ; EGFR ; APOPTOSIS ; CELLS ; ACTIVATION ; RESISTANCE ; EXPRESSION ; DIAGNOSIS
研究领域[WOS]	Research & Experimental Medicine
WOS记录号	WOS:000427107300012
引用统计	被引频次：50[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.yic.ac.cn/handle/133337/24027
专题	中国科学院海岸带环境过程与生态修复重点实验室
通讯作者	Yu, Fabiao; Chen, Lingxin; Lv, Changjun
作者单位	1.Binzhou Med Univ Hosp, Dept Resp Med, Binzhou 256603, Peoples R China 2.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China 3.Binzhou Med Univ, Inst Mol Med, Med Res Ctr, Yantai 264003, Peoples R China 4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Song, Xinyu,Han, Xiaoyue,Yu, Fabiao,et al. Polyamine-Targeting Gefitinib Prodrug and its Near-Infrared Fluorescent Theranostic Derivative for Monitoring Drug Delivery and Lung Cancer Therapy[J]. THERANOSTICS,2018,8(8):2217-2228.
APA	Song, Xinyu,Han, Xiaoyue,Yu, Fabiao,Zhang, Xiaoyu,Chen, Lingxin,&Lv, Changjun.(2018).Polyamine-Targeting Gefitinib Prodrug and its Near-Infrared Fluorescent Theranostic Derivative for Monitoring Drug Delivery and Lung Cancer Therapy.THERANOSTICS,8(8),2217-2228.
MLA	Song, Xinyu,et al."Polyamine-Targeting Gefitinib Prodrug and its Near-Infrared Fluorescent Theranostic Derivative for Monitoring Drug Delivery and Lung Cancer Therapy".THERANOSTICS 8.8(2018):2217-2228.