Inulin with different degrees of polymerization modulates composition of intestinal microbiota in mice
Zhu, Limeng1,2; Qin, Song1; Zhai, Shixiang1; Gao, Yonglin3; Li, Lili1
发表期刊FEMS MICROBIOLOGY LETTERS
ISSN0378-1097
2017-05-01
卷号364期号:10
关键词Butyrate-producing Bacteria Degrees Of Polymerization Fructo-oligosaccharides Intestinal Microbiota Inulin Metagenomics
DOI10.1093/femsle/fnx075
英文摘要The study aimed to analyze the global influences of dietary inulin with different degrees of polymerization (DP) on intestinal microbial communities. Six-week-old male C57BL/6J mice were treated with fructo-oligosaccharides and inulin for 6 weeks. Fecal samples were obtained at time point 0 and 6th week. 16S rRNA sequence analysis was used to measure intestinal microbiota performed on the Illumina MiSeq platform. Influences of dietary inulin on intestinal microbiota were more complex effects than bifidogenic effects, relative abundance of butyrate-producing bacteria increased after interventions. Akkermansia muciniphila, belonging to mucin-degrading species, became a dominant species in Verrucomicrobia phylum after treatment with fructo-oligosaccharides and inulin. Modulation effects of intestinal microbiota were positively correlated with DP. Lower DP interventions exhibited better effects than higher DP treatment on stimulation of probiotics. We hypothesized that Akkermansia muciniphila played an important role on maintaining balance between mucin and short chain fatty acids.
文章类型Article
资助机构National Natural Science Foundation of China(21306221) ; National Key Technology Research and Development Program of China(2013BAB01B01) ; Science and Technology Development Program of Shandong Province(2010GSF10208)
收录类别SCI
语种英语
关键词[WOS]CHAIN FATTY-ACID ; BUTYRATE-PRODUCING BACTERIA ; GUT MICROBIOTA ; AKKERMANSIA-MUCINIPHILA ; HEALTH ; STIMULATION ; DIVERSITY ; DIETARY ; COLON ; RATS
研究领域[WOS]Microbiology
WOS记录号WOS:000404534500010
引用统计
被引频次:56[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.yic.ac.cn/handle/133337/22546
专题海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室
作者单位1.Chinese Acad Sci, Yantai Inst Costal Zone Res, 17 Chunhui Rd, Yantai 264003, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
3.Yantai Univ, Yantai 264003, Peoples R China
推荐引用方式
GB/T 7714
Zhu, Limeng,Qin, Song,Zhai, Shixiang,et al. Inulin with different degrees of polymerization modulates composition of intestinal microbiota in mice[J]. FEMS MICROBIOLOGY LETTERS,2017,364(10).
APA Zhu, Limeng,Qin, Song,Zhai, Shixiang,Gao, Yonglin,&Li, Lili.(2017).Inulin with different degrees of polymerization modulates composition of intestinal microbiota in mice.FEMS MICROBIOLOGY LETTERS,364(10).
MLA Zhu, Limeng,et al."Inulin with different degrees of polymerization modulates composition of intestinal microbiota in mice".FEMS MICROBIOLOGY LETTERS 364.10(2017).
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Zhu, Limeng]的文章
[Qin, Song]的文章
[Zhai, Shixiang]的文章
百度学术
百度学术中相似的文章
[Zhu, Limeng]的文章
[Qin, Song]的文章
[Zhai, Shixiang]的文章
必应学术
必应学术中相似的文章
[Zhu, Limeng]的文章
[Qin, Song]的文章
[Zhai, Shixiang]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。