Institutional Repository of Key Laboratory of Coastal Zone Environmental Processes, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences (KLCEP)
Quantum Dot-Based Molecularly Imprinted Polymers on Three-Dimensional Origami Paper Microfluidic Chip for Fluorescence Detection of Phycocyanin | |
Li, Bowei1; Zhang, Zhong1,2; Qi, Ji1,4; Zhou, Na1; Qin, Song1; Choo, Jaebum3; Chen, Lingxin1,4; Chen, LX (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China.; Choo, J (reprint author), Hanyang Univ, Dept Bionano Engn, Ansan 426791, South Korea.; Chen, LX (reprint author), Yantai Univ, Sch Environm & Mat Engn, Yantai 264005, Peoples R China. jbchoo@hanyang.ac.kr; lxchen@yic.ac.cn | |
发表期刊 | ACS SENSORS |
ISSN | 2379-3694 |
2017-02-01 | |
卷号 | 2期号:2页码:243-250 |
关键词 | Paper-based Microfluidic Devices Molecularly Imprinted Polymers (Mips) Quantum Dot Phycocyanin Fluorescence |
DOI | 10.1021/acssensors.6b00664 |
产权排序 | [Li, Bowei; Zhang, Zhong; Qi, Ji; Zhou, Na; Qin, Song; Chen, Lingxin] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China; [Zhang, Zhong] Shaanxi Normal Univ, Coll Food Engn & Nutr Sci, Xian 710119, Peoples R China; [Choo, Jaebum] Hanyang Univ, Dept Bionano Engn, Ansan 426791, South Korea; [Qi, Ji; Chen, Lingxin] Yantai Univ, Sch Environm & Mat Engn, Yantai 264005, Peoples R China |
作者部门 | 中科院海岸带环境过程与生态修复重点实验室 |
英文摘要 | In this work, we developed a novel strategy using fluorescent quantum dots (QDs) combined with molecularly imprinted polymers (MIPs) on three-dimensional (3D) origami paper-based microfluidic devices for specific recognition and sensitive detection of phycocyanin. This method can realize the liquid phase of QDs@MIPs being transferred to the solid-phase paper base and achieve easy portability for the analysis. Under optimal conditions, we successfully demonstrated the proposed paper@QDs@MIP5 3D microfluidic chip for the sensitive and selective detection of phycocyanin protein target in a simple and robust manner. Our results revealed that the method exhibited a dynamic response to phycocyanin in the range of 10-50 mg/L with a limit of detection of 2 mg/L. Importantly, this device could provide quantitative information very conveniently and show great potential to be further extended to the detection of other proteins or biomarkers for environmental and food safety research. |
文章类型 | Article |
资助机构 | National Defense Science and Technology Innovation Project of Chinese Academy of Sciences(CXJJ-16M254) ; Science and Technology Development Plan of Yantai(2015ZH087) ; Natural Science Research Foundation of China(21205131 ; Fundamental Research Funds for the Central Universities in China(GK201603099) ; Shanxi Province Agricultural Science and Technology Innovation ; Key Project(2016NY-181) ; Korea Health Industry Development Institute (KHIDI) - Ministry of Health and Welfare, Korea(H116C2129) ; 41406125) |
收录类别 | SCI |
语种 | 英语 |
关键词[WOS] | METHYLAMINO-L-ALANINE ; NEUROTOXIC AMINO-ACID ; CYANOBACTERIAL TOXINS ; SIGNAL AMPLIFICATION ; DEVICE ; MICROSPHERES ; COOCCURRENCE ; RECOGNITION ; POPULATIONS ; BIOASSAYS |
研究领域[WOS] | Chemistry ; Science & Technology - Other Topics |
WOS记录号 | WOS:000395047000009 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.yic.ac.cn/handle/133337/22072 |
专题 | 中国科学院海岸带环境过程与生态修复重点实验室 海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室 |
通讯作者 | Chen, LX (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China.; Choo, J (reprint author), Hanyang Univ, Dept Bionano Engn, Ansan 426791, South Korea.; Chen, LX (reprint author), Yantai Univ, Sch Environm & Mat Engn, Yantai 264005, Peoples R China. jbchoo@hanyang.ac.kr; lxchen@yic.ac.cn |
作者单位 | 1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China 2.Shaanxi Normal Univ, Coll Food Engn & Nutr Sci, Xian 710119, Peoples R China 3.Hanyang Univ, Dept Bionano Engn, Ansan 426791, South Korea 4.Yantai Univ, Sch Environm & Mat Engn, Yantai 264005, Peoples R China |
推荐引用方式 GB/T 7714 | Li, Bowei,Zhang, Zhong,Qi, Ji,et al. Quantum Dot-Based Molecularly Imprinted Polymers on Three-Dimensional Origami Paper Microfluidic Chip for Fluorescence Detection of Phycocyanin[J]. ACS SENSORS,2017,2(2):243-250. |
APA | Li, Bowei.,Zhang, Zhong.,Qi, Ji.,Zhou, Na.,Qin, Song.,...&lxchen@yic.ac.cn.(2017).Quantum Dot-Based Molecularly Imprinted Polymers on Three-Dimensional Origami Paper Microfluidic Chip for Fluorescence Detection of Phycocyanin.ACS SENSORS,2(2),243-250. |
MLA | Li, Bowei,et al."Quantum Dot-Based Molecularly Imprinted Polymers on Three-Dimensional Origami Paper Microfluidic Chip for Fluorescence Detection of Phycocyanin".ACS SENSORS 2.2(2017):243-250. |
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