Novel 1,2,3-triazolium-functionalized starch derivatives: Synthesis, characterization, and evaluation of antifungal property | |
Tan, Wenqiang![]() ![]() ![]() | |
Source Publication | CARBOHYDRATE POLYMERS
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ISSN | 0144-8617 |
2017-03-15 | |
Volume | 160Pages:163-171 |
Keyword | Starch Chemical Modification Antifungal Activity Click Chemistry Characterization 1 2 3-triazolium |
DOI | 10.1016/j.carbpol.2016.12.060 |
Department | 海岸带生物学与生物资源利用所重点实验室 |
Abstract | Four novel 1,2,3-triazolium-functionalized starch derivatives were synthesized by N-alkylating the precursor starch derivatives with 1,2,3-triazole with iodomethane based on cuprous-catalyzed azide-alkyne cycloaddition (CuAAC). The detailed structural characterization was investigated by means of FTIR, UV-vis, H-1 NMR, and C-13 NMR spectra. The antifungal activities of starch derivatives against Colletotrichum lagenarium, Fusarium oxysporum, and Watermelon fusarium, were then assayed by hypha measurement in vitro. The fungicidal assessment revealed that compared with starch and starch derivatives with 1,2,3-triazole, 1,2,3-triazolium-functionalized starch derivatives displayed tremendously enhanced antifungal activity. Especially, the inhibitory indices of 6-(4-hydroxymethy1-3-methyl-1,2,3-triazolium1-yl)-6-deoxy starch iodine (2a) with against the tested plant threatening fungi attained 70% above at 1.0 mg/mL. It was also found that their antifungal activity profiles were dependent on the variation in alkyl chain length. As novel 1,2,3-triazolium-functionalized starch derivatives could be prepared efficiently and exhibited superduper antifungal activity, this synthetic strategy might provide an effective way and notion to prepare novel antifungal biomaterials. (C) 2016 Elsevier Ltd. All rights reserved. |
Subtype | Article |
Funding Organization | National Natural Science Foundation of China(41576156) ; Shandong Province Science and Technology Development Plan(2015GSF121045) ; Yantai Science and Technology Development Plan(2015ZH078) ; Public Science and Technology Research Funds Projects of Ocean(201505022-3) |
Indexed By | SCI |
Language | 英语 |
WOS Keyword | CLICK CHEMISTRY ; STRUCTURAL-PROPERTIES ; ANTIBACTERIAL ACTIVITY ; BIOLOGICAL EVALUATION ; AZOLE DERIVATIVES ; GRAFTED-CHITOSAN ; AGENTS ; AMMONIUM ; DESIGN ; COPOLYMERS |
WOS Research Area | Chemistry ; Polymer Science |
WOS ID | WOS:000393246800019 |
Citation statistics | |
Document Type | 期刊论文 |
Identifier | http://ir.yic.ac.cn/handle/133337/21939 |
Collection | 海岸带生物学与生物资源利用重点实验室_海岸带生物资源高效利用研究与发展中心 海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室 中科院海岸带环境过程与生态修复重点实验室_污染过程与控制实验室 |
Corresponding Author | Guo, ZY (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China. zhanyongguo@hotmail.com |
Affiliation | 1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Yantai Univ, Coll Life Sci, Yantai 264005, Peoples R China |
Recommended Citation GB/T 7714 | Tan, Wenqiang,Li, Qing,Dong, Fang,et al. Novel 1,2,3-triazolium-functionalized starch derivatives: Synthesis, characterization, and evaluation of antifungal property[J]. CARBOHYDRATE POLYMERS,2017,160:163-171. |
APA | Tan, Wenqiang.,Li, Qing.,Dong, Fang.,Qiu, Shuai.,Zhang, Jingjing.,...&Guo, ZY .(2017).Novel 1,2,3-triazolium-functionalized starch derivatives: Synthesis, characterization, and evaluation of antifungal property.CARBOHYDRATE POLYMERS,160,163-171. |
MLA | Tan, Wenqiang,et al."Novel 1,2,3-triazolium-functionalized starch derivatives: Synthesis, characterization, and evaluation of antifungal property".CARBOHYDRATE POLYMERS 160(2017):163-171. |
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