| Chemical constituents and their bioactivities from the fruits of Vitex negundo var. cannabifolia | |
Fang, Sheng-Tao ; Kong, Na-Na; Yan, Bing-Fei; Yang, Cui-Yun; Wang, Jian-Hua; Liu, Su-Jing; Jin, Hai -Zhu; Xia, Chuan-Hai; Fang, ST
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| Source Publication | NATURAL PRODUCT RESEARCH
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| ISSN | 1478-6419 |
| 2016 | |
| Volume | 30Issue:24Pages:2856-2860 |
| Keyword | Vitex Negundo Var. Cannabifolia Chemical Constituent Cytotoxicity Brine Shrimp Lethality |
| DOI | 10.1080/14786419.2016.1174228 |
| Contribution Rank | [Fang, Sheng-Tao; Kong, Na-Na; Yan, Bing-Fei; Yang, Cui-Yun; Wang, Jian-Hua; Liu, Su-Jing; Xia, Chuan-Hai] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Biol Resources Utilizat, Yantai, Peoples R China; [Yan, Bing-Fei; Jin, Hai -Zhu] Yantai Univ, Chem & Chem Engn Coll, Yantai, Peoples R China; [Kong, Na-Na] Univ Chinese Acad Sci, Coll Resources & Environm, Beijing, Peoples R China |
| Department | 海岸带生物学与生物资源利用所重点实验室 |
| Abstract | Phytochemical investigation of the fruits of Vitex negundo var. cannabifolia led to the isolation of 22 compounds (1-22). Their structures were elucidated mainly by spectroscopic analysis and comparison with the literature data. Among them, compounds 1 and 2 were two new artificial lignans. Primary bioassay showed that the polymethoxyflavones 9-12 displayed moderate-to-weak cytotoxicity against human HepG2 and rat C6 cell lines, while the triterpenoids 13-17 exhibited significant brine shrimp lethality with LC50 values of 7.5-29.4 mu M. |
| Subtype | Article |
| Indexed By | SCI |
| Language | 英语 |
| WOS Keyword | SEEDS ; LIGNANS |
| WOS Research Area | Chemistry ; Pharmacology & Pharmacy |
| WOS ID | WOS:000388974300018 |
| Funding Organization | National Natural Science Foundation of China(21202198) ; Projects of Natural Key Technology Research and Development Program of the Ministry of Science and Technology of China(2011BAC02B04) |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.yic.ac.cn/handle/133337/19267 |
| Collection | 海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室 |
| Corresponding Author | Fang, ST |
| Affiliation | 1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Biol Resources Utilizat, Yantai, Peoples R China 2.Yantai Univ, Chem & Chem Engn Coll, Yantai, Peoples R China 3.Yantai Univ, Chem & Chem Engn Coll, Yantai, Peoples R China 4.Univ Chinese Acad Sci, Coll Resources & Environm, Beijing, Peoples R China |
| Recommended Citation GB/T 7714 | Fang, Sheng-Tao,Kong, Na-Na,Yan, Bing-Fei,et al. Chemical constituents and their bioactivities from the fruits of Vitex negundo var. cannabifolia[J]. NATURAL PRODUCT RESEARCH,2016,30(24):2856-2860. |
| APA | Fang, Sheng-Tao.,Kong, Na-Na.,Yan, Bing-Fei.,Yang, Cui-Yun.,Wang, Jian-Hua.,...&Fang, ST.(2016).Chemical constituents and their bioactivities from the fruits of Vitex negundo var. cannabifolia.NATURAL PRODUCT RESEARCH,30(24),2856-2860. |
| MLA | Fang, Sheng-Tao,et al."Chemical constituents and their bioactivities from the fruits of Vitex negundo var. cannabifolia".NATURAL PRODUCT RESEARCH 30.24(2016):2856-2860. |
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| Chemical constituent（817KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Download | |
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