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题名:
Chemical constituents and their bioactivities from the fruits of Vitex negundo var. cannabifolia
作者: Fang, Sheng-Tao; Kong, Na-Na; Yan, Bing-Fei; Yang, Cui-Yun; Wang, Jian-Hua; Liu, Su-Jing; Jin, Hai -Zhu; Xia, Chuan-Hai
刊名: NATURAL PRODUCT RESEARCH
ISSN号: 1478-6419
出版日期: 2016
卷号: 30, 期号:24, 页码:2856-2860
关键词: Vitex negundo var. cannabifolia ; chemical constituent ; cytotoxicity ; brine shrimp lethality
DOI: 10.1080/14786419.2016.1174228
产权排序: [Fang, Sheng-Tao; Kong, Na-Na; Yan, Bing-Fei; Yang, Cui-Yun; Wang, Jian-Hua; Liu, Su-Jing; Xia, Chuan-Hai] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Biol Resources Utilizat, Yantai, Peoples R China; [Yan, Bing-Fei; Jin, Hai -Zhu] Yantai Univ, Chem & Chem Engn Coll, Yantai, Peoples R China; [Kong, Na-Na] Univ Chinese Acad Sci, Coll Resources & Environm, Beijing, Peoples R China
通讯作者: Fang, ST
作者部门: 海岸带生物学与生物资源利用所重点实验室 
英文摘要: Phytochemical investigation of the fruits of Vitex negundo var. cannabifolia led to the isolation of 22 compounds (1-22). Their structures were elucidated mainly by spectroscopic analysis and comparison with the literature data. Among them, compounds 1 and 2 were two new artificial lignans. Primary bioassay showed that the polymethoxyflavones 9-12 displayed moderate-to-weak cytotoxicity against human HepG2 and rat C6 cell lines, while the triterpenoids 13-17 exhibited significant brine shrimp lethality with LC50 values of 7.5-29.4 mu M.
研究领域[WOS]: Chemistry ; Pharmacology & Pharmacy
项目资助者: National Natural Science Foundation of China(21202198) ; Projects of Natural Key Technology Research and Development Program of the Ministry of Science and Technology of China(2011BAC02B04)
关键词[WOS]: SEEDS ; LIGNANS
文章类型: Article
收录类别: SCI
语种: 英语
WOS记录号: WOS:000388974300018
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.yic.ac.cn/handle/133337/19267
Appears in Collections:海岸带生物学与生物资源利用所重点实验室_期刊论文

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作者单位: 1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Biol Resources Utilizat, Yantai, Peoples R China
2.Yantai Univ, Chem & Chem Engn Coll, Yantai, Peoples R China
3.Yantai Univ, Chem & Chem Engn Coll, Yantai, Peoples R China
4.Univ Chinese Acad Sci, Coll Resources & Environm, Beijing, Peoples R China

Recommended Citation:
Fang, Sheng-Tao,Kong, Na-Na,Yan, Bing-Fei,et al. Chemical constituents and their bioactivities from the fruits of Vitex negundo var. cannabifolia[J]. NATURAL PRODUCT RESEARCH,2016,30(24):2856-2860.
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文件名: Chemical constituents and their bioactivities from the fruits of Vitex negundo var. cannabifolia.pdf
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