Chemical constituents and their bioactivities from the fruits of Vitex negundo var. cannabifolia
Fang, Sheng-Tao; Kong, Na-Na; Yan, Bing-Fei; Yang, Cui-Yun; Wang, Jian-Hua; Liu, Su-Jing; Jin, Hai -Zhu; Xia, Chuan-Hai; Fang, ST
2016
发表期刊NATURAL PRODUCT RESEARCH
ISSN1478-6419
卷号30期号:24页码:2856-2860
产权排序[Fang, Sheng-Tao; Kong, Na-Na; Yan, Bing-Fei; Yang, Cui-Yun; Wang, Jian-Hua; Liu, Su-Jing; Xia, Chuan-Hai] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Biol Resources Utilizat, Yantai, Peoples R China; [Yan, Bing-Fei; Jin, Hai -Zhu] Yantai Univ, Chem & Chem Engn Coll, Yantai, Peoples R China; [Kong, Na-Na] Univ Chinese Acad Sci, Coll Resources & Environm, Beijing, Peoples R China
摘要Phytochemical investigation of the fruits of Vitex negundo var. cannabifolia led to the isolation of 22 compounds (1-22). Their structures were elucidated mainly by spectroscopic analysis and comparison with the literature data. Among them, compounds 1 and 2 were two new artificial lignans. Primary bioassay showed that the polymethoxyflavones 9-12 displayed moderate-to-weak cytotoxicity against human HepG2 and rat C6 cell lines, while the triterpenoids 13-17 exhibited significant brine shrimp lethality with LC50 values of 7.5-29.4 mu M.
关键词Vitex Negundo Var. Cannabifolia Chemical Constituent Cytotoxicity Brine Shrimp Lethality
作者部门海岸带生物学与生物资源利用所重点实验室 
DOI10.1080/14786419.2016.1174228
项目资助者National Natural Science Foundation of China(21202198) ; Projects of Natural Key Technology Research and Development Program of the Ministry of Science and Technology of China(2011BAC02B04)
收录类别SCI
关键词[WOS]SEEDS ; LIGNANS
文章类型Article
语种英语
WOS研究方向Chemistry ; Pharmacology & Pharmacy
WOS记录号WOS:000388974300018
引用统计
被引频次:3[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.yic.ac.cn/handle/133337/19267
专题海岸带生物学与生物资源利用所重点实验室
通讯作者Fang, ST
作者单位1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Biol Resources Utilizat, Yantai, Peoples R China
2.Yantai Univ, Chem & Chem Engn Coll, Yantai, Peoples R China
3.Yantai Univ, Chem & Chem Engn Coll, Yantai, Peoples R China
4.Univ Chinese Acad Sci, Coll Resources & Environm, Beijing, Peoples R China
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GB/T 7714
Fang, Sheng-Tao,Kong, Na-Na,Yan, Bing-Fei,et al. Chemical constituents and their bioactivities from the fruits of Vitex negundo var. cannabifolia[J]. NATURAL PRODUCT RESEARCH,2016,30(24):2856-2860.
APA Fang, Sheng-Tao.,Kong, Na-Na.,Yan, Bing-Fei.,Yang, Cui-Yun.,Wang, Jian-Hua.,...&Fang, ST.(2016).Chemical constituents and their bioactivities from the fruits of Vitex negundo var. cannabifolia.NATURAL PRODUCT RESEARCH,30(24),2856-2860.
MLA Fang, Sheng-Tao,et al."Chemical constituents and their bioactivities from the fruits of Vitex negundo var. cannabifolia".NATURAL PRODUCT RESEARCH 30.24(2016):2856-2860.
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