YIC-IR  > 中科院海岸带环境过程与生态修复重点实验室
A Three-Dimensional Origami Paper-Based Device for Potentiometric Biosensing
Ding, JW; Li, BW; Chen, LX; Qin, W; Qin, W (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Shandong, Peoples R China.; Qin, W (reprint author), YICCAS, Shandong Prov Key Lab Coastal Environm Proc, Yantai 264003, Shandong, Peoples R China. Email:wqin@yic.ac.cn
2016-10-10
Source PublicationANGEWANDTE CHEMIE-INTERNATIONAL EDITION
ISSN1433-7851
Volume55Issue:42Pages:13033-13037
Contribution Rank[Ding, Jiawang; Li, Bowei; Chen, Lingxin; Qin, Wei] Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Shandong, Peoples R China; [Ding, Jiawang; Li, Bowei; Chen, Lingxin; Qin, Wei] YICCAS, Shandong Prov Key Lab Coastal Environm Proc, Yantai 264003, Shandong, Peoples R China
AbstractCurrent paper-based potentiometric ion-sensing platforms are planar devices used for clinically relevant ions. These devices, however, have not been designed for the potentiometric biosensing of proteins or small molecule analytes. A three-dimensional origami paper-based device, in which a solid-contact ion-selective electrode is integrated with an all-solid-state reference electrode, is described for the first time. The device is made by impregnation of paper with appropriate bioreceptors and reporting reagents on different zones. By folding and unfolding the paper structures, versatile potentiometric bioassays can be performed. A USB-controlled miniaturized electrochemical detector can be used for simple and in situ measurements. Using butyrylcholinesterase as a model enzyme, the device has been successfully applied to the detection of enzyme activities and organophosphate pesticides involved in the enzymatic system as inhibitors. The proposed 3D origami paper device allows the potentiometric biosensing of proteins and small molecules in a simple, portable, and cost-effective way.
KeywordBiosensors Enzyme-based Assays Origami Paper-based Devices Potentiometry
Department中科院海岸带环境过程与生态修复重点实验室
DOI10.1002/anie.201606268
Funding OrganizationNational Natural Science Foundation of China(21575158 ; Strategic Priority Research Program of the Chinese Academy of Sciences(XDA11020702) ; Youth Innovation Promotion Association of CAS(2013139) ; Taishan Scholar Program of Shandong Province ; 21475148 ; 21205131)
Indexed BySCI
WOS KeywordION-SELECTIVE ELECTRODES ; SOLID-CONTACT ; ELECTROANALYTICAL DEVICES ; ELECTROCHEMICAL DETECTION ; MICROFLUIDIC DEVICES ; MEMBRANE ELECTRODES ; CARBON NANOTUBES ; DETECTION LIMITS ; SENSORS ; PLATFORM
SubtypeArticle
Language英语
WOS Research AreaChemistry
WOS IDWOS:000385799200013
Citation statistics
Document Type期刊论文
Identifierhttp://ir.yic.ac.cn/handle/133337/17468
Collection中科院海岸带环境过程与生态修复重点实验室
Corresponding AuthorQin, W (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Shandong, Peoples R China.; Qin, W (reprint author), YICCAS, Shandong Prov Key Lab Coastal Environm Proc, Yantai 264003, Shandong, Peoples R China. Email:wqin@yic.ac.cn
Recommended Citation
GB/T 7714
Ding, JW,Li, BW,Chen, LX,et al. A Three-Dimensional Origami Paper-Based Device for Potentiometric Biosensing[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,2016,55(42):13033-13037.
APA Ding, JW,Li, BW,Chen, LX,Qin, W,Qin, W ,&Qin, W .(2016).A Three-Dimensional Origami Paper-Based Device for Potentiometric Biosensing.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,55(42),13033-13037.
MLA Ding, JW,et al."A Three-Dimensional Origami Paper-Based Device for Potentiometric Biosensing".ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 55.42(2016):13033-13037.
Files in This Item: Download All
File Name/Size DocType Version Access License
A Three-Dimensional (1130KB)期刊论文作者接受稿开放获取CC BY-NC-SAView Download
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Ding, JW]'s Articles
[Li, BW]'s Articles
[Chen, LX]'s Articles
Baidu academic
Similar articles in Baidu academic
[Ding, JW]'s Articles
[Li, BW]'s Articles
[Chen, LX]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Ding, JW]'s Articles
[Li, BW]'s Articles
[Chen, LX]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: A Three-Dimensional Origami Paper-Based Device for Potentiometric Biosensing.pdf
Format: Adobe PDF
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.