| Alkaloids from an algicolous strain of Talaromyces sp. | |
Yang, HB; Li, F ; Ji, NY; Li, F (reprint author), Qingdao Univ Sci & Technol, Coll Chem & Mol Engn, Qingdao 266042, Peoples R China.; Ji, NY (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China. iceli_2003@126.com; nyji@yic.ac.cn
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| 2016-03-01 | |
| Source Publication | CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY
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| ISSN | 0254-4059 |
| Volume | 34Issue:2Pages:367-371 |
| Contribution Rank | [Yang Haibin; Li Fang] Qingdao Univ Sci & Technol, Coll Chem & Mol Engn, Qingdao 266042, Peoples R China; [Yang Haibin; Ji Naiyun] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China |
| Abstract | Compounds isolated and identified in a culture of the alga-endophytic fungus Talaromyces sp. cf-16 included two naturally occurring alkaloids, 2-[(S)-hydroxy(phenyl)methyl]-3-methylquinazolin-4(3H)-one (1a) and 2-[(R)-hydroxy(phenyl)methyl]-3-methylquinazolin-4(3H)-one (1b), that were identified for the first time. In addition, seven known compounds (2-8) were obtained from the culture. Following chiral column chromatography, compounds 1a and 1b were identified as enantiomers by spectroscopic analyses and quantum chemical calculations. Bioassay results showed that 5 was more toxic to brine shrimp than the other compounds, and that 3-6 could inhibit Staphylococcus aureus. |
| Keyword | Talaromyces Sp. Alkaloid Chiral Separation Quantum Chemical Calculation Bioactivity |
| Department | 海岸带生物学与生物资源利用所重点实验室 |
| DOI | 10.1007/s00343-015-4316-2 |
| Funding Organization | National Key Technology Research and Development Program for Agriculture(2012BAD32B09) ; National Natural Science Foundation of China(41106137 ; Taishan Scholar Program of Shandong Province ; Chinese Academy of Sciences for Key Topics in Innovation Engineering(KZCX2-YW-QN209) ; 41106136) |
| Indexed By | SCI |
| WOS Keyword | ELECTRONIC CIRCULAR-DICHROISM ; ABSOLUTE-CONFIGURATIONS ; ASPERGILLUS-VERSICOLOR ; OPTICAL-ROTATION ; NATURAL-PRODUCTS ; ROQUEFORTINE ; METABOLITES ; MYCOTOXIN |
| Subtype | Article |
| Language | 英语 |
| WOS Research Area | Marine & Freshwater Biology ; Oceanography |
| WOS ID | WOS:000371607000011 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.yic.ac.cn/handle/133337/10846 |
| Collection | 海岸带生物学与生物资源保护实验室 |
| Corresponding Author | Li, F (reprint author), Qingdao Univ Sci & Technol, Coll Chem & Mol Engn, Qingdao 266042, Peoples R China.; Ji, NY (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China. iceli_2003@126.com; nyji@yic.ac.cn |
| Affiliation | 1.Qingdao Univ Sci & Technol, Coll Chem & Mol Engn 2.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat |
| Recommended Citation GB/T 7714 | Yang, HB,Li, F,Ji, NY,et al. Alkaloids from an algicolous strain of Talaromyces sp.[J]. CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,2016,34(2):367-371. |
| APA | Yang, HB,Li, F,Ji, NY,Li, F ,Ji, NY ,&nyji@yic.ac.cn.(2016).Alkaloids from an algicolous strain of Talaromyces sp..CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,34(2),367-371. |
| MLA | Yang, HB,et al."Alkaloids from an algicolous strain of Talaromyces sp.".CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY 34.2(2016):367-371. |
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| Alkaloids from an al（545KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Download | |
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