Alkaloids from an algicolous strain of Talaromyces sp.

doi:10.1007/s00343-015-4316-2

	Alkaloids from an algicolous strain of Talaromyces sp.
	Yang, HB ; Li, F ; Ji, NY ; Li, F (reprint author), Qingdao Univ Sci & Technol, Coll Chem & Mol Engn, Qingdao 266042, Peoples R China.; Ji, NY (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China. iceli_2003@126.com ; nyji@yic.ac.cn
	2016-03-01
发表期刊	CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY
ISSN	0254-4059
卷号	34 期号:2 页码:367-371
产权排序	[Yang Haibin; Li Fang] Qingdao Univ Sci & Technol, Coll Chem & Mol Engn, Qingdao 266042, Peoples R China; [Yang Haibin; Ji Naiyun] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China
摘要	Compounds isolated and identified in a culture of the alga-endophytic fungus Talaromyces sp. cf-16 included two naturally occurring alkaloids, 2-[(S)-hydroxy(phenyl)methyl]-3-methylquinazolin-4(3H)-one (1a) and 2-[(R)-hydroxy(phenyl)methyl]-3-methylquinazolin-4(3H)-one (1b), that were identified for the first time. In addition, seven known compounds (2-8) were obtained from the culture. Following chiral column chromatography, compounds 1a and 1b were identified as enantiomers by spectroscopic analyses and quantum chemical calculations. Bioassay results showed that 5 was more toxic to brine shrimp than the other compounds, and that 3-6 could inhibit Staphylococcus aureus.
关键词	Talaromyces Sp. Alkaloid Chiral Separation Quantum Chemical Calculation Bioactivity
作者部门	海岸带生物学与生物资源利用所重点实验室
DOI	10.1007/s00343-015-4316-2
项目资助者	National Key Technology Research and Development Program for Agriculture(2012BAD32B09) ; National Natural Science Foundation of China(41106137 ; Taishan Scholar Program of Shandong Province ; Chinese Academy of Sciences for Key Topics in Innovation Engineering(KZCX2-YW-QN209) ; 41106136)
收录类别	SCI
关键词[WOS]	ELECTRONIC CIRCULAR-DICHROISM ; ABSOLUTE-CONFIGURATIONS ; ASPERGILLUS-VERSICOLOR ; OPTICAL-ROTATION ; NATURAL-PRODUCTS ; ROQUEFORTINE ; METABOLITES ; MYCOTOXIN
文章类型	Article
语种	英语
WOS研究方向	Marine & Freshwater Biology ; Oceanography
WOS记录号	WOS:000371607000011
引用统计	被引频次：4[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.yic.ac.cn/handle/133337/10846
专题	海岸带生物学与生物资源利用所重点实验室
通讯作者	Li, F (reprint author), Qingdao Univ Sci & Technol, Coll Chem & Mol Engn, Qingdao 266042, Peoples R China.; Ji, NY (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China. iceli_2003@126.com; nyji@yic.ac.cn
作者单位	1.Qingdao Univ Sci & Technol, Coll Chem & Mol Engn 2.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat
推荐引用方式 GB/T 7714	Yang, HB,Li, F,Ji, NY,et al. Alkaloids from an algicolous strain of Talaromyces sp.[J]. CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,2016,34(2):367-371.
APA	Yang, HB,Li, F,Ji, NY,Li, F ,Ji, NY ,&nyji@yic.ac.cn.(2016).Alkaloids from an algicolous strain of Talaromyces sp..CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,34(2),367-371.
MLA	Yang, HB,et al."Alkaloids from an algicolous strain of Talaromyces sp.".CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY 34.2(2016):367-371.

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